Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2. (Q46754854)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28977421 AND SRC:MED&resulttype=core&format=json

31 March 2020

title

Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2 (English)

1 reference

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31 March 2020

3

1 reference

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31 March 2020

Gianluca Tell

10

1 reference

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31 March 2020

author name string

Matilde Clarissa Malfatti

1

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31 March 2020

Sathya Balachander

2

1 reference

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31 March 2020

Kyung Duk Koh

4

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31 March 2020

Christine Saint-Pierre

5

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31 March 2020

Didier Gasparutto

6

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31 March 2020

Hyongi Chon

7

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31 March 2020

Robert J Crouch

8

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31 March 2020

Francesca Storici

9

1 reference

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31 March 2020

language of work or name

English

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publication date

1 November 2017

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31 March 2020

published in

Nucleic Acids Research

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31 March 2020

volume

45

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31 March 2020

issue

19

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31 March 2020

page(s)

11193-11212

1 reference

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Creative Commons Attribution-NonCommercial 4.0 International

31 March 2020

copyright license

start time

18 August 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5737539/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer

24 May 2018

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Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms

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24 May 2018

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24 May 2018

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24 May 2018

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24 May 2018

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Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity

24 May 2018

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24 May 2018

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24 May 2018

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24 May 2018

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24 May 2018

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USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β

24 May 2018

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Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage

24 May 2018

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Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.

24 May 2018

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24 May 2018

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Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers.

24 May 2018

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Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?

24 May 2018

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Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

24 May 2018

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Ribonuclease H: the enzymes in eukaryotes

24 May 2018

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APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

24 May 2018

1 reference

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Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells.

24 May 2018

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Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex

24 May 2018

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Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision

24 May 2018

1 reference

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Nucleic acid oxidation in Alzheimer disease

24 May 2018

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Clinical and molecular phenotype of Aicardi-Goutieres syndrome

24 May 2018

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Base-excision repair of oxidative DNA damage

24 May 2018

1 reference

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24 May 2018

RNA-templated DNA repair

1 reference

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Oxidized messenger RNA induces translation errors

24 May 2018

1 reference

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The chemical stability of abasic RNA compared to abasic DNA.

24 May 2018

1 reference

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Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

24 May 2018

1 reference

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Germline susceptibility to colorectal cancer due to base-excision repair gene defects

24 May 2018

1 reference

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Two essential but distinct functions of the mammalian abasic endonuclease

24 May 2018

1 reference

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The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.

24 May 2018

1 reference

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Pokeweed antiviral protein binds to the cap structure of eukaryotic mRNA and depurinates the mRNA downstream of the cap.

24 May 2018

1 reference

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Base excision repair in nuclear and mitochondrial DNA.

24 May 2018

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Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism

24 May 2018

1 reference

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Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step

24 May 2018

1 reference

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Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein

24 May 2018

1 reference

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The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis

24 May 2018

1 reference

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DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

24 May 2018

1 reference

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Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress

24 May 2018

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Enzymatic N-riboside scission in RNA and RNA precursors.

24 May 2018

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Instability and decay of the primary structure of DNA

24 May 2018

1 reference

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Physiological concentrations of purines and pyrimidines

24 May 2018

1 reference

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Oxidative base damage in RNA detected by reverse transcriptase

24 May 2018

1 reference

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Rate of depurination of native deoxyribonucleic acid

24 May 2018

1 reference

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Mutagenesis by apurinic/apyrimidinic sites

24 May 2018

1 reference

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Ribonucleotide-induced helical alteration in DNA prevents nucleosome formation

24 May 2018

1 reference

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Chemical synthesis of a biologically active natural tRNA with its minor bases

24 May 2018

1 reference

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Impact of Ribonucleotide Backbone on Translesion Synthesis and Repair of 7,8-Dihydro-8-oxoguanine.

24 May 2018

1 reference

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Measuring the elasticity of ribonucleotide(s)-containing DNA molecules using AFM.

15 August 2018

1 reference

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Human apurinic/apyrimidinic endonuclease 1 (APE1) has 3' RNA phosphatase and 3' exoribonuclease activities.

15 August 2018

1 reference

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Mispaired rNMPs in DNA are mutagenic and are targets of mismatch repair and RNases H

15 August 2018

1 reference

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RNA-driven genetic changes in bacteria and in human cells

15 August 2018

1 reference

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Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5737539

Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5737539

Ape1 abasic endonuclease activity is regulated by magnesium and potassium concentrations and is robust on alternative DNA structures

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5737539

The exonuclease activity of human apurinic/apyrimidinic endonuclease (APE1). Biochemical properties and inhibition by the natural dinucleotide Gp4G.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5737539

Binding capacity of human YB-1 protein for RNA containing 8-oxoguanine

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5737539

The role of Mg2 and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5737539

RNA intrusions change DNA elastic properties and structure

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5737539

Formation of ribonucleotides in DNA modified by oxidative damage in vitro and in vivo. Characterization by 32P-postlabeling

3 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28977421

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular biology. Ribose--an internal threat to DNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28977421

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKX723

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28977421 AND SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28977421 AND SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

28977421

1 reference