PIK3CA mutations rarely demonstrate genotypic intratumoral heterogeneity and are selected for in breast cancer progression. (Q46614726)

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2 February 2020

title

PIK3CA mutations rarely demonstrate genotypic intratumoral heterogeneity and are selected for in breast cancer progression (English)

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2 February 2020

3

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2 February 2020

Mary Ellen Moynahan

5

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2 February 2020

author name string

Kevin Kalinsky

1

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2 February 2020

Adriana Heguy

2

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2 February 2020

Sujata Patil

4

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2 February 2020

language of work or name

English

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publication date

27 May 2011

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Breast Cancer Research and Treatment

2 February 2020

published in

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2 February 2020

volume

129

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2 February 2020

issue

2

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2 February 2020

page(s)

635-643

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

2 February 2020

cites work

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PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer

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PIK3CA mutation associates with improved outcome in breast cancer.

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Sequential steroid hormone receptor measurements in primary breast cancer with and without intervening primary chemotherapy.

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Genotypic intratumoral heterogeneity in breast carcinoma with HER2/neu amplification: evaluation according to ASCO/CAP criteria.

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Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer

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Loss of HER2 amplification following trastuzumab-based neoadjuvant systemic therapy and survival outcomes

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Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome

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Genetic alterations during colorectal-tumor development

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Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma

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PIK3CA mutations mostly begin to develop in ductal carcinoma of the breast

21 January 2018

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PIK3CA mutations in in situ and invasive breast carcinomas

21 January 2018

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PIK3CA Mutations May Be Discordant between Primary and Corresponding Metastatic Disease in Breast Cancer

21 January 2018

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Genomic and biological characterization of exon 4 KRAS mutations in human cancer

21 January 2018

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Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern

21 January 2018

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Gene expression profiles of estrogen receptor-positive and estrogen receptor-negative breast cancers are detectable in histologically normal breast epithelium

21 January 2018

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Mammary field cancerization: molecular evidence and clinical importance

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Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

21 January 2018

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10.1007/S10549-011-1601-4

21 January 2018

Identifiers

DOI

1 reference

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2 February 2020

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