Semi-quantitative CYP2D6 gene doses in relation to metabolic ratios of psychotropics (Q46540903)

23 December 2017

title

Semi-quantitative CYP2D6 gene doses in relation to metabolic ratios of psychotropics (English)

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23 December 2017

author name string

John W J Hinrichs

1

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23 December 2017

Harriët M Loovers

2

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23 December 2017

Bart Scholten

3

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23 December 2017

Jan van der Weide

4

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23 December 2017

publication date

14 June 2008

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23 December 2017

European Journal of Clinical Pharmacology

published in

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23 December 2017

volume

64

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23 December 2017

issue

10

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23 December 2017

page(s)

979-986

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23 December 2017

Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007/S00228-008-0509-3

Therapeutic drug monitoring of antidepressants and cytochrome p450 genotyping in general practice

21 January 2018

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12 December 2020

Effect of the CYP2D6*10 genotype on venlafaxine pharmacokinetics in healthy adult volunteers

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12 December 2020

Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers

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A high-performance liquid chromatographic method for the simultaneous determination of venlafaxine and O-desmethylvenlafaxine in biological fluids

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12 December 2020

O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants

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12 December 2020

Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes

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12 December 2020

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

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12 December 2020

A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.

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12 December 2020

The disposition of fluoxetine but not sertraline is altered in poor metabolizers of debrisoquin

1 reference

12 December 2020

CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages

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12 December 2020

CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism

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12 December 2020

Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6.1, 2D6.2, 2D6.10, and 2D6.17 allelic isoforms

1 reference

12 December 2020

Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR

1 reference

12 December 2020

Detection of CYP2D6 polymorphisms *9, *10, and *41 using ARMS-PCR and their allelic frequencies in 400 psychiatric patients

1 reference

12 December 2020

Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans

1 reference

12 December 2020

Impaired expression of CYP2D6 in intermediate metabolizers carrying the *41 allele caused by the intronic SNP 2988G>A: evidence for modulation of splicing events.

1 reference

12 December 2020

Determination of risperidone and its major metabolite 9-hydroxyrisperidone in human plasma by reversed-phase liquid chromatography with ultraviolet detection

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12 December 2020

Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population

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12 December 2020

Effects of CYP2C19 genotype and CYP2C9 on fluoxetine N-demethylation in human liver microsomes

1 reference

12 December 2020

Simultaneous determination of citalopram, fluoxetine, paroxetine and their metabolites in plasma and whole blood by high-performance liquid chromatography with ultraviolet and fluorescence detection

1 reference

12 December 2020

Metabolic ratios of psychotropics as indication of cytochrome P450 2D6/2C19 genotype

1 reference

12 December 2020

Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6

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12 December 2020

A multifamily study on the relationship between CYP2C19 genotype and S-mephenytoin oxidation phenotype

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12 December 2020

O-Dealkylation of fluoxetine in relation to CYP2C19 gene dose and involvement of CYP3A4 in human liver microsomes

1 reference

12 December 2020

Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone

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12 December 2020

Concentrations of the enantiomers of fluoxetine and norfluoxetine after multiple doses of fluoxetine in cytochrome P4502D6 poor and extensive metabolizers.

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12 December 2020

Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients

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12 December 2020

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype

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12 December 2020

Venlafaxine serum levels and CYP2D6 genotype

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12 December 2020

Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4

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12 December 2020

Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population

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12 December 2020

Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy

1 reference

12 December 2020

Venlafaxine oxidation in vitro is catalysed by CYP2D6.

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12 December 2020

Comparison of two CYP2D6 genotyping methods and assessment of genotype-phenotype relationships

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12 December 2020

10.1007/S00228-008-0509-3

Identifiers

DOI

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23 December 2017

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23 December 2017