Human Neuronal Calcium Sensor-1 Protein Avoids Histidine Residues To Decrease pH Sensitivity (Q46439263)

http://europepmc.org/abstract/PMC/6413881

2 July 2019

title

Human Neuronal Calcium Sensor-1 Protein Avoids Histidine Residues To Decrease pH Sensitivity (English)

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http://europepmc.org/abstract/PMC/6413881

2 July 2019

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6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28030949 AND SRC:MED&resulttype=core&format=json

9 June 2020

Buyong Ma

4

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9 June 2020

5

Ruth Nussinov

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9 June 2020

author name string

Yehong Gong

1

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9 June 2020

Yuzhen Zhu

2

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9 June 2020

Yu Zou

3

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9 June 2020

language of work or name

English

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publication date

17 January 2017

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http://europepmc.org/abstract/PMC/6413881

2 July 2019

number of pages

10

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Journal of Physical Chemistry B

inferred from page(s)

published in

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9 June 2020

volume

121

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issue

3

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9 June 2020

page(s)

508-517

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Folding funnels and binding mechanisms

9 June 2020

cites work

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Regulation of neurite outgrowth mediated by neuronal calcium sensor-1 and inositol 1,4,5-trisphosphate receptor in nerve growth cones

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NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory

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Frequenin/NCS-1 and the Ca2 -channel alpha1-subunit co-regulate synaptic transmission and nerve-terminal growth

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12 December 2020

Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorder

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Neuronal Calcium Sensor-1 Regulation of Calcium Channels, Secretion, and Neuronal Outgrowth

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Optimal Salt Bridge for Trp-Cage Stabilization

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The unique Alzheimer's β-amyloid triangular fibril has a cavity along the fibril axis under physiological conditions

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Molecular structure and target recognition of neuronal calcium sensor proteins

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12 December 2020

Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra‐molecular communication pathways

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The C-terminal tail of human neuronal calcium sensor 1 regulates the conformational stability of the Ca²⁺₋ activated state

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The Neuronal Calcium Sensor protein Acrocalcin: a potential target of calmodulin regulation during development in the coral Acropora millepora

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Environmental alkalinity sensing mediated by the transmembrane guanylyl cyclase GCY-14 in C. elegans

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12 December 2020

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12 December 2020

The structure of neuronal calcium sensor-1 in solution revealed by molecular dynamics simulations

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More antitumor efficacy of the PI3K inhibitor GDC-0941 in breast cancer with PIK3CA mutation or HER2 amplification status in vitro

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12 December 2020

R102Q mutation shifts the salt-bridge network and reduces the structural flexibility of human neuronal calcium sensor-1 protein

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The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas

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Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC).

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Effects of the C-Terminal Tail on the Conformational Dynamics of Human Neuronal Calcium Sensor-1 Protein.

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Critical Nucleus Structure and Aggregation Mechanism of the C-terminal Fragment of Copper-Zinc Superoxide Dismutase Protein

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Temperature-Dependent Conformational Properties of Human Neuronal Calcium Sensor-1 Protein Revealed by All-Atom Simulations.

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Are buried salt bridges important for protein stability and conformational specificity?

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Identifiers

DOI

10.1021/ACS.JPCB.6B11094

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28030949 AND SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28030949 AND SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

28030949

1 reference