A Genetic Analysis of the Caenorhabditis elegans Detoxification Response (Q46379821)

19 June 2018

title

A Genetic Analysis of the Caenorhabditis elegans Detoxification Response (English)

1 reference

19 June 2018

main subject

Caenorhabditis elegans

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author

Michael W. Krause

4

1 reference

PubMed publication ID

28428286

21 December 2017

http://europepmc.org/abstract/MED/28428286

author name string

Tetsunari Fukushige

1

1 reference

19 June 2018

Harold E Smith

2

1 reference

19 June 2018

Johji Miwa

3

1 reference

19 June 2018

John A Hanover

5

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19 June 2018

language of work or name

English

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publication date

19 April 2017

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19 June 2018

published in

Genetics

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19 June 2018

volume

206

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19 June 2018

issue

2

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19 June 2018

page(s)

939-952

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19 June 2018

F-Box Protein XREP-4 Is a New Regulator of the Oxidative Stress Response in Caenorhabditis elegans

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The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK

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Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway

22 June 2018

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Characterization of skn-1/wdr-23 phenotypes in Caenorhabditis elegans; pleiotrophy, aging, glutathione, and interactions with other longevity pathways

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SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation

22 June 2018

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Genome-wide screening identifies new genes required for stress-induced phase 2 detoxification gene expression in animals.

22 June 2018

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mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity

22 June 2018

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Regulation of synaptic nlg-1/neuroligin abundance by the skn-1/Nrf stress response pathway protects against oxidative stress

22 June 2018

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Adaptive capacity to bacterial diet modulates aging in C. elegans

22 June 2018

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SKN-1/Nrf, a new unfolded protein response factor?

22 June 2018

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Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

22 June 2018

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Adaptive and specialised transcriptional responses to xenobiotic stress in Caenorhabditis elegans are regulated by nuclear hormone receptors

22 June 2018

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The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

22 June 2018

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An ultra high-throughput, whole-animal screen for small molecule modulators of a specific genetic pathway in Caenorhabditis elegans

22 June 2018

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The conserved SKN-1/Nrf2 stress response pathway regulates synaptic function in Caenorhabditis elegans

22 June 2018

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A core metabolic enzyme mediates resistance to phosphine gas.

22 June 2018

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Mitochondrial SKN-1/Nrf mediates a conserved starvation response

22 June 2018

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Unique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistance

22 June 2018

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A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans

22 June 2018

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The three-dimensional structural basis of type II hyperprolinemia

22 June 2018

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22 June 2018

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22 June 2018

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A cadmium toxicity assay using stress responsive Caenorhabditis elegans mutant strains

22 June 2018

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Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity

22 June 2018

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22 June 2018

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RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.

22 June 2018

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22 June 2018

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Genetic and cellular characterization of Caenorhabditis elegans mutants abnormal in the regulation of many phase II enzymes

22 June 2018

1 reference

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Stress-activated cap'n'collar transcription factors in aging and human disease

22 June 2018

1 reference

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Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor

22 June 2018

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22 June 2018

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Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

A protein domain-based interactome network for C. elegans early embryogenesis

22 June 2018

1 reference

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Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes

22 June 2018

1 reference

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The F-box protein family.

22 June 2018

1 reference

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Regulatory mechanisms of cellular response to oxidative stress

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

A new DNA-binding motif in the Skn-1 binding domain-DNA complex

22 June 2018

1 reference

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SKN-1 domain folding and basic region monomer stabilization upon DNA binding

22 June 2018

1 reference

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Skn-1: evidence for a bipartite recognition helix in DNA binding

22 June 2018

1 reference

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Natural variation and copulatory plug formation in Caenorhabditis elegans

22 June 2018

1 reference

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

22 June 2018

1 reference

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Type II hyperprolinaemia in a pedigree of Irish travellers (nomads)

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

The enzymes of detoxication

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Proline Catabolism Modulates Innate Immunity in Caenorhabditis elegans

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Inborn errors of proline metabolism.

15 August 2018

1 reference

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A rapid and inexpensive method to screen for common foods that reduce the action of acrylamide, a harmful substance in food

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Acrylamide-responsive genes in the nematode Caenorhabditis elegans

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Extremely low dose of acrylamide decreases lifespan in Caenorhabditis elegans

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

Multiple Skp1-related proteins in Caenorhabditis elegans: diverse patterns of interaction with Cullins and F-box proteins

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499196

10.1534/GENETICS.117.202515

15 August 2018

Identifiers

DOI

1 reference

19 June 2018

PMC publication ID

5499196

1 reference

19 June 2018

PubMed publication ID

28428286

1 reference

19 June 2018