CB(1) and CB(2) cannabinoid receptors mediate different aspects of delta-9-tetrahydrocannabinol (THC)-induced T helper cell shift following immune activation by Legionella pneumophila infection (Q46367174)

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English	CB(1) and CB(2) cannabinoid receptors mediate different aspects of delta-9-tetrahydrocannabinol (THC)-induced T helper cell shift following immune activation by Legionella pneumophila infection	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

CB(1) and CB(2) cannabinoid receptors mediate different aspects of delta-9-tetrahydrocannabinol (THC)-induced T helper cell shift following immune activation by Legionella pneumophila infection (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

tetrahydrocannabinol

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cannabinoid receptor

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Legionella pneumophila

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author name string

Catherine A Newton

1

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

Ping-Jen Chou

2

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

Izabella Perkins

3

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

Thomas W Klein

4

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

publication date

16 September 2008

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

Journal of Neuroimmune Pharmacology

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

4

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

1

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

92-102

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

Delta 9-tetrahydrocannabinol treatment suppresses immunity and early IFN-gamma, IL-12, and IL-12 receptor beta 2 responses to Legionella pneumophila infection

1 reference

https://api.crossref.org/works/10.1007/S11481-008-9126-2

21 January 2018

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

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https://api.crossref.org/works/10.1007/S11481-008-9126-2

21 January 2018

Distinct structural requirements of GATA-3 for the regulation of thymocyte and Th2 cell differentiation.

1 reference

https://api.crossref.org/works/10.1007/S11481-008-9126-2

21 January 2018

Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation.

1 reference

https://api.crossref.org/works/10.1007/S11481-008-9126-2

21 January 2018

Delta-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway

1 reference

https://api.crossref.org/works/10.1007/S11481-008-9126-2

21 January 2018

Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion

1 reference

https://api.crossref.org/works/10.1007/S11481-008-9126-2

21 January 2018

Formation of B and T cell subsets require the cannabinoid receptor CB2.

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Notch and the immune system

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Induction of interleukin-2 receptor alpha gene by delta9-tetrahydrocannabinol is mediated by nuclear factor kappaB and CB1 cannabinoid receptor

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Pharmacology of cannabinoid CB1 and CB2 receptors.

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Signaling pathways in Th2 development

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Differential expression of cannabinoid CB(2) receptor mRNA in mouse immune cell subpopulations and following B cell stimulation

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Induction of interleukin-4 (IL-4) by legionella pneumophila infection in BALB/c mice and regulation of tumor necrosis factor alpha, IL-6, and IL-1beta

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Interleukin-4 can induce interleukin-4 production in dendritic cells.

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Anti-CD40, anti-CD3, and IL-2 stimulation induce contrasting changes in CB1 mRNA expression in mouse splenocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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The THC-induced suppression of Th1 polarization in response to Legionella pneumophila infection is not mediated by increases in corticosterone and PGE2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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The function role of GATA-3 in Th1 and Th2 differentiation.

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Transcriptional regulation of the cannabinoid receptor type 1 gene in T cells by cannabinoids

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cannabinoid receptors in Delta-9-tetrahydrocannabinol suppression of IL-12p40 in mouse bone marrow-derived dendritic cells infected with Legionella pneumophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Regulation of interleukin-12 production by G-protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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In silico patent searching reveals a new cannabinoid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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inferred from PubMed ID database lookup

Role of gamma interferon in induction of natural killer activity by Legionella pneumophila in vitro and in an experimental murine infection model

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Molecular and cellular control of T1/T2 immunity at the interface between antimicrobial defense and immune pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Cannabinoid-based drugs as anti-inflammatory therapeutics

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Presence and regulation of the endocannabinoid system in human dendritic cells

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Dendritic cell regulation of TH1-TH2 development

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Delta 9-tetrahydrocannabinol injection induces cytokine-mediated mortality of mice infected with Legionella pneumophila

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Therapeutic potential of cannabinoid-based drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Cannabinoid treatment suppresses the T-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Legionella pneumophila suppresses interleukin-12 production by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Legionella pneumophilaSuppresses Macrophage Interleukin-12 Production by Activating the p42/44 Mitogen-Activated Protein Kinase Cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Host-pathogen interactions: subversion and utilization of the NF-kappa B pathway during infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Cannabinoid-induced immune suppression and modulation of antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/8/34 in the absence and presence of Delta9-tetrahydrocannabinol

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Notch directly regulates Gata3 expression during T helper 2 cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Attenuation of allergic contact dermatitis through the endocannabinoid system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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Basophils and type 2 immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

based on heuristic

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International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

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https://pubmed.ncbi.nlm.nih.gov/18792785

12 December 2020

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Identifiers

10.1007/S11481-008-9126-2

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18792785

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