Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains (Q46344376)

21 December 2017

title

Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains (English)

1 reference

21 December 2017

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consumer product safety

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21447365

28 November 2024

author name string

R. J. Safford

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21447365

28 November 2024

A. O. Aptula

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21447365

28 November 2024

N. Gilmour

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21447365

28 November 2024

language of work or name

English

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publication date

3 April 2011

1 reference

21 December 2017

full work available at URL

https://api.elsevier.com/content/article/PII:S0273230011000626?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

https://api.elsevier.com/content/article/PII:S0273230011000626?httpAccept=text/plain

28 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Regulatory Toxicology and Pharmacology

28 November 2024

published in

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21 December 2017

volume

60

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21 December 2017

issue

2

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21 December 2017

page(s)

218-224

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21 December 2017

Identifying and characterizing chemical skin sensitizers without animal testing: Colipa's research and method development program

cites work

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Reactivity profiling: covalent modification of single nucleophile peptides for skin sensitization risk assessment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Mechanistic applicability domains for nonanimal-based prediction of toxicological end points: general principles and application to reactive toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

The local lymph node assay: a viable alternative to currently accepted skin sensitization tests

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Strategies for identifying false positive responses in predictive skin sensitization tests

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Use of the local lymph node assay for the estimation of relative contact allergenic potency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Local lymph node assay - validation, conduct and use in practice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Updating the skin sensitization in vitro data assessment paradigm in 2009.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Predictive identification of human skin sensitization thresholds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Understanding fragrance allergy using an exposure-based risk assessment approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

A future approach to measuring relative skin sensitising potency: a proposal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

The local lymph node assay: past, present and future

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Feasibility study to support a threshold of sensitization concern concept in risk assessment based on human data

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Guinea-pig contact sensitization assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

The murine local lymph node assay: regulatory and potency considerations under REACH.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

TIMES-SS—A promising tool for the assessment of skin sensitization hazard. A characterization with respect to the OECD validation principles for (Q)SARs and an external evaluation for predictivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

TIMES-SS—A Mechanistic Evaluation of an External Validation Study Using Reaction Chemistry Principles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Oxidation of resin acids in colophony (rosin) and its implications for patch testing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

The Dermal Sensitisation Threshold- a TTC approach for allergic contact dermatitis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods

7 January 2021

14

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

Assuring consumer safety without animal testing: a feasibility case study for skin sensitisation

28 November 2024

26

1 reference

https://api.crossref.org/works/10.1016/J.YRTPH.2011.03.009

28 November 2024

Identifiers

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21 December 2017

release_ekivnixj4ffyxaguayz6gnzpqy

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https://api.fatcat.wiki/v0/release/ekivnixj4ffyxaguayz6gnzpqy

mapped directly with Wikidata item

24 November 2022

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21 December 2017