Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells (Q46314249)

21 December 2017

title

Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells (English)

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21 December 2017

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9

Carsten J Kirschning

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21 December 2017

Hermann Wagner

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object named as

Hermann Wagner

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21 December 2017

author name string

Frank Schmitz

1

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21 December 2017

Antje Heit

2

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21 December 2017

Stefan Dreher

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21 December 2017

Katharina Eisenächer

4

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21 December 2017

Jörg Mages

5

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21 December 2017

Tobias Haas

6

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21 December 2017

Anne Krug

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21 December 2017

Klaus-Peter Janssen

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21 December 2017

language of work or name

English

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publication date

1 November 2008

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21 December 2017

European Journal of Immunology

published in

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21 December 2017

volume

38

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21 December 2017

issue

11

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21 December 2017

page(s)

2981-2992

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21 December 2017

Akt decreases lymphocyte apoptosis and improves survival in sepsis

cites work

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https://api.crossref.org/works/10.1002/EJI.200838761

Phosphoinositide 3-kinase: diverse roles in immune cell activation

21 January 2018

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Role of phosphoinositide 3-kinase in innate immunity

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

TOR signaling in growth and metabolism

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Identification of a conserved motif required for mTOR signaling

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Toll-like receptor signalling

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Pathogen recognition and innate immunity

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

An Atomic Model of the Interferon-β Enhanceosome

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Proinflammatory and Anti-inflammatory Cytokines as Mediators in the Pathogenesis of Septic Shock

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Versatile inducible activation system of Akt/PKB signaling pathway in mice

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Active caspase-1 is a regulator of unconventional protein secretion

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Inhibition of human B lymphocyte cell cycle progression and differentiation by rapamycin

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Translational control of the innate immune response through IRF-7

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

IRF-7 is the master regulator of type-I interferon-dependent immune responses

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-induced IL-23 expression in human macrophages

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

AMPK phosphorylation of raptor mediates a metabolic checkpoint

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https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-β production in myeloid dendritic cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200838761

7 January 2021

Identifiers

DOI

10.1002/EJI.200838761

1 reference

21 December 2017

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21 December 2017