Retinal pigment epithelium cholesterol efflux mediated by the 18 kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration (Q46296050)

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English	Retinal pigment epithelium cholesterol efflux mediated by the 18 kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

Retinal pigment epithelium cholesterol efflux mediated by the 18 kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

author name string

Lincoln Biswas

1

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

Xinzhi Zhou

2

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

Baljean Dhillon

3

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

Annette Graham

4

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

Xinhua Shu

5

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

publication date

24 August 2017

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

Human Molecular Genetics

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Europe PubMed Central

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21 December 2017

http://europepmc.org/abstract/MED/28973423

26

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

22

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

4327-4339

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

Prevalence of age-related macular degeneration in the United States

1 reference

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21 January 2018

Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression

1 reference

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21 January 2018

Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy

1 reference

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21 January 2018

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

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Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

1 reference

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21 January 2018

Mechanisms for cellular cholesterol transport: defects and human disease

1 reference

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21 January 2018

Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype

1 reference

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21 January 2018

Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis

1 reference

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21 January 2018

Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation.

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21 January 2018

Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis

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21 January 2018

High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture

1 reference

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21 January 2018

The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells

1 reference

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21 January 2018

Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration

1 reference

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Regulated expression of apolipoprotein E by human retinal pigment epithelial cells

1 reference

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Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization

1 reference

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21 January 2018

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

1 reference

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21 January 2018

Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands

1 reference

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21 January 2018

Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies

1 reference

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21 January 2018

Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Macroglia-microglia interactions via TSPO signaling regulates microglial activation in the mouse retina

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Spatial distribution of the pathways of cholesterol homeostasis in human retina

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

1 reference

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21 January 2018

Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines

1 reference

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21 January 2018

Translocator Protein (TSPO) Affects Mitochondrial Fatty Acid Oxidation in Steroidogenic Cells

1 reference

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21 January 2018

Cholesterol in the retina: the best is yet to come.

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Mitochondrial regulation of macrophage cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Translocator Protein 18 kDa (TSPO): An Old Protein with New Functions?

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins

1 reference

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21 January 2018

Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

RPE cells internalize low-density lipoprotein (LDL) and oxidized LDL (oxLDL) in large quantities in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Accumulation of oxidized lipid-protein complexes alters phagosome maturation in retinal pigment epithelium

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Decreased membrane complement regulators in the retinal pigmented epithelium contributes to age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Protective responses to sublytic complement in the retinal pigment epithelium

1 reference

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21 January 2018

Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration.

1 reference

https://api.crossref.org/works/10.1093/HMG/DDX319

21 January 2018

TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model

1 reference

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21 January 2018

Regression of Some High-risk Features of Age-related Macular Degeneration (AMD) in Patients Receiving Intensive Statin Treatment

1 reference

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21 January 2018

Nanosecond laser therapy reverses pathologic and molecular changes in age-related macular degeneration without retinal damage.

1 reference

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21 January 2018

Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration

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Sorsby Fundus Dystrophy: Novel Mutations, Novel Phenotypic Characteristics, and Treatment Outcomes.

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21 January 2018

Identifiers

10.1093/HMG/DDX319

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/28973423

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