Enantioselective determination of mexiletine and its metabolites p-hydroxymexiletine and hydroxymethylmexiletine in rat plasma by normal-phase liquid chromatography-tandem mass spectrometry: application to pharmacokinetics. (Q46273668)

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scientific article published in July 2009

Language	Label	Description	Also known as
English	Enantioselective determination of mexiletine and its metabolites p-hydroxymexiletine and hydroxymethylmexiletine in rat plasma by normal-phase liquid chromatography-tandem mass spectrometry: application to pharmacokinetics.	scientific article published in July 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18973279 AND SRC:MED&resulttype=core&format=json

25 December 2019

Enantioselective determination of mexiletine and its metabolites p-hydroxymexiletine and hydroxymethylmexiletine in rat plasma by normal-phase liquid chromatography-tandem mass spectrometry: application to pharmacokinetics (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18973279 AND SRC:MED&resulttype=core&format=json

25 December 2019

enantioselectivity

1 reference

based on heuristic

inferred from title

liquid chromatography-tandem mass spectrometry

1 reference

based on heuristic

inferred from title

Maria Paula Marques

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18973279 AND SRC:MED&resulttype=core&format=json

25 December 2019

Eduardo B. Coelho

4

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Europe PubMed Central

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25 December 2019

Vera Lucia Lanchote

5

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25 December 2019

author name string

Ana Leonor Pardo Campos Godoy

1

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Europe PubMed Central

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25 December 2019

Caio Cesar Parisi

2

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25 December 2019

publication date

1 July 2009

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25 December 2019

1 reference

Europe PubMed Central

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25 December 2019

21

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25 December 2019

7

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25 December 2019

648-656

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25 December 2019

Stereoselective disposition of mexiletine in man

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

21 January 2018

Efficacy and Safety of Mexiletine in the Treatment of Painful Diabetic Neuropathy. The Mexiletine Study Group

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of stereoselectivity on the pharmacokinetics and pharmacodynamics of antiarrhythmic drugs

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Facile entry to (-)-(R)- and ( )-(S)-mexiletine

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of CYP1A2 in mexiletine metabolism

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Stereoselective analysis of the enantiomers of mexiletine by high-performance liquid chromatography using fluorescence detection and study of their stereoselective disposition in man

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Tissue distribution of mexiletine enantiomers in rats

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved high-performance liquid chromatographic assay for the stereoselective determination of mexiletine in plasma

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct analysis of the enantiomers of mexiletine and its metabolites in plasma and urine using an HPLC-CSP

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

High-performance liquid chromatographic analysis using a highly sensitive fluorogenic reagent, 2-anthroyl chloride, and stereoselective determination of the enantiomers of mexiletine in human serum

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the enantiomeric composition of mexiletine and its four hydroxylated metabolites in urine by enantioselective capillary gas chromatography

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of enantiomers of chiral phenethylamine drugs by capillary gas chromatography/mass spectrometry/flame-ionization detection and pre-column chiral derivatization

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

High-performance liquid chromatographic assay for mexiletine enantiomers in human plasma

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics of mexiletine enantiomers in healthy human subjects. A study of the in vivo serum protein binding, salivary excretion and red blood cell distribution of the enantiomers

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

High-performance liquid chromatographic determination of mexiletine enantiomers in plasma using direct and indirect enantioselective separations

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Enantioselective determination of the hydroxylated metabolites of mexiletine in human plasma

1 reference

https://api.crossref.org/works/10.1002/CHIR.20650

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CHIR.20650

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18973279 AND SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18973279 AND SRC:MED&resulttype=core&format=json

25 December 2019

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