Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice. (Q46221935)

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2 March 2020

title

Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice (English)

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2 March 2020

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2 March 2020

Elena Gammella

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2 March 2020

Stefania Recalcati

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2 March 2020

author name string

Víctor Díaz

1

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2 March 2020

Paolo Santambrogio

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2 March 2020

Arianne Monge Naldi

5

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2 March 2020

Johannes Vogel

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2 March 2020

Max Gassmann

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2 March 2020

language of work or name

English

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publication date

21 October 2013

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2 March 2020

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volume

58

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issue

6

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page(s)

2122-2132

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

2 March 2020

cites work

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Hepcidin and iron regulation, 10 years later

21 January 2018

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BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

21 January 2018

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Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

21 January 2018

1 reference

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

21 January 2018

1 reference

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice

21 January 2018

1 reference

Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin

21 January 2018

1 reference

Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project

21 January 2018

1 reference

Alterations of systemic and muscle iron metabolism in human subjects treated with low-dose recombinant erythropoietin

21 January 2018

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Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha

21 January 2018

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Suppression of hepcidin during anemia requires erythropoietic activity

21 January 2018

1 reference

Erythropoietin stimulation decreases hepcidin expression through hematopoietic activity on bone marrow cells in mice

21 January 2018

1 reference

Iron and erythropoiesis: a dual relationship

21 January 2018

1 reference

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

21 January 2018

1 reference

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

21 January 2018

1 reference

Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli.

21 January 2018

1 reference

β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

21 January 2018

1 reference

Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression.

21 January 2018

1 reference

Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin

21 January 2018

1 reference

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

21 January 2018

1 reference

Enhanced erythro-phagocytosis in polycythemic mice overexpressing erythropoietin

21 January 2018

1 reference

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

21 January 2018

1 reference

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

1 reference

Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.

21 January 2018

1 reference

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

21 January 2018

1 reference

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis

21 January 2018

1 reference

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

21 January 2018

1 reference

EPO-mediated reduction in Hamp expression in vivo corrects iron deficiency anaemia in TMPRSS6 deficiency.

21 January 2018

1 reference

Ferroportin-mediated iron transport: expression and regulation

21 January 2018

1 reference

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

21 January 2018

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The serine protease TMPRSS6 is required to sense iron deficiency

21 January 2018

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Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

21 January 2018

1 reference

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

21 January 2018

1 reference

Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis

21 January 2018

1 reference

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.

21 January 2018

1 reference

Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle

21 January 2018

1 reference

Regulation of hepcidin expression at high altitude

21 January 2018

1 reference

Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HEP.26550

1 reference

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release_ftyv6xc7tfdqrei76oe2rsg7ha

2 March 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

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