Impact of cyclic hypoxia on HIF-1alpha regulation in endothelial cells--new insights for anti-tumor treatments (Q46200912)

20 December 2017

title

Impact of cyclic hypoxia on HIF-1alpha regulation in endothelial cells--new insights for anti-tumor treatments (English)

1 reference

20 December 2017

0 references

0 references

Philippe Martinive

1

1 reference

20 December 2017

Florence Defresne

2

1 reference

20 December 2017

Elise Quaghebeur

3

1 reference

20 December 2017

Géraldine Daneau

4

1 reference

20 December 2017

Nathalie Crokart

5

1 reference

20 December 2017

Vincent Grégoire

6

1 reference

20 December 2017

Bernard Gallez

7

1 reference

20 December 2017

Chantal Dessy

8

1 reference

20 December 2017

Olivier Feron

9

1 reference

20 December 2017

language of work or name

English

0 references

publication date

10 December 2008

1 reference

20 December 2017

published in

FEBS Journal

1 reference

20 December 2017

volume

276

1 reference

20 December 2017

issue

2

1 reference

20 December 2017

page(s)

509-518

1 reference

20 December 2017

Targeting HIF-1 for cancer therapy

cites work

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Physiological and pathological responses to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Harnessing the response to tissue hypoxia: HIF-1 alpha and therapeutic angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Oxygen sensing by HIF hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Cytokines and hormones in the regulation of hypoxia inducible factor-1alpha (HIF-1alpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Regulation of HIF-1alpha stability through S-nitrosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Mitochondria as signaling organelles in the vascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Hypoxia in tumors: a paradigm for the approach to biochemical and physiologic heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Concepts of oxygen transport at the microcirculatory level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Temporal heterogeneity in oxygen tension in human melanoma xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Fluctuations in pO2 in poorly and well-oxygenated spontaneous canine tumors before and during fractionated radiation therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Why do cancers have high aerobic glycolysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia: implications for anticancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

How does blood oxygen level-dependent (BOLD) contrast correlate with oxygen partial pressure (pO2) inside tumors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

The role of vessel maturation and vessel functionality in spontaneous fluctuations of T2*-weighted GRE signal within tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

The pervasive presence of fluctuating oxygenation in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Hsp90 ensures the transition from the early Ca2 -dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2008.06798.X

10.1111/J.1742-4658.2008.06798.X

21 January 2018

Identifiers

DOI

1 reference

20 December 2017

1 reference

20 December 2017