Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study (Q46133006)

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scientific article published on 4 February 2009

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English	Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study	scientific article published on 4 February 2009

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study (English)

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

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ChEBI release 2020-05-28

bipolar depression

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Perry F Renshaw

6

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Perry F Renshaw

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

2

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In Kyoon Lyoo

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

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Sujung J Yoon

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

Charlotte Haws

3

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

Tae-Suk Kim

4

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

Bruce M Cohen

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19 December 2017

http://europepmc.org/abstract/MED/19194376

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publication date

4 February 2009

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

Neuropsychopharmacology

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

34

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

7

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

1810-1818

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

Cytidine 5'-diphosphocholine (CDP-choline) in stroke and other CNS disorders

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Citicoline: neuroprotective mechanisms in cerebral ischemia

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Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine

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Effects of acute and chronic lamotrigine treatment on basal and stimulated extracellular amino acids in the hippocampus of freely moving rats

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Quantitation of proton NMR spectra of the human brain using tissue water as an internal concentration reference

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Bipolar disorder--focus on bipolar II disorder and mixed depression

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Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre

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Uridine and cytidine in the brain: their transport and utilization

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Initiation and adaptation: a paradigm for understanding psychotropic drug action

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Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients

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Antidepressants and the risk of suicidal behaviors

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Mitochondrial dysfunction in bipolar disorder

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Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments

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Beyond monoamines: glutamatergic function in mood disorders

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Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neuroglial cultures from rat cortex

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Pyrimidine pathways in health and disease

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Glutamate transporters in neurologic disease

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Interaction of CDP-choline with synaptosomal transport of biogenic amines and their precursors in vitro and in vivo in the rat corpus striatum

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In vivo short echo time 1H-magnetic resonance spectroscopic imaging (MRSI) of the temporal lobes

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Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex

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CDP-choline prevents glutamate-mediated cell death in cerebellar granule neurons.

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Do recent efficacy data on the drug treatment of acute bipolar depression support the position that drugs other than antidepressants are the treatment of choice? A conceptual review

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A long-lasting facilitation of hippocampal neurotransmission via a phospholipase A2 signaling pathway

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Glial reduction in the subgenual prefrontal cortex in mood disorders

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Phosphoinositide signaling in human brain

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Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS

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Automatic quantitation of localized in vivo 1H spectra with LCModel

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CDP-choline reduces dopaminergic cell loss induced by MPP( ) and glutamate in primary mesencephalic cell culture

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Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells

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Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder

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In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function.

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Effectiveness of adjunctive antidepressant treatment for bipolar depression

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Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms

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Nucleotide metabolism in rat brain

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Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy

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Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research

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Treatment of bipolar depression

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A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group.

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Differential Outcome of Pure Manic, Mixed/Cycling, and Pure Depressive Episodes in Patients With Bipolar Illness

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Biochemistry and physiology of n-3 fatty acids

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1 reference

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Bipolar disorder

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Effect of cytidine on membrane phospholipid synthesis in rat striatal slices

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7 January 2021

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10.1038/NPP.2009.2

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19194376

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