Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer. (Q46055974)

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6 March 2020

title

Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer (English)

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1

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author name string

William P Harris

2

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6 March 2020

J Thaddeus Beck

3

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6 March 2020

Boris A Berdov

4

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Stephanie A Wagner

5

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Eduard M Pshevlotsky

6

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Sergei A Tjulandin

7

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Oleg A Gladkov

8

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Randall F Holcombe

9

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Ronald Korn

10

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Natarajan Raghunand

11

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Samuel Dychter

12

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Ping Jiang

13

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H Michael Shepard

14

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Craig E Devoe

15

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language of work or name

English

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publication date

26 January 2016

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6 March 2020

published in

Clinical Cancer Research

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volume

22

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issue

12

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page(s)

2848-2854

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Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).

6 March 2020

cites work

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12 December 2020

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

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12 December 2020

Molecules Involved in Mammalian Sperm-Egg Interaction

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12 December 2020

The impact of extracellular matrix on the chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy.

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12 December 2020

Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival

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12 December 2020

Pancreatic cancer and thromboembolic disease.

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12 December 2020

Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

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12 December 2020

Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models

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12 December 2020

Pooled Survival and Response Data From Phase III Randomized Controlled Trials for Gemcitabine-based Regimes in the Treatment of Advanced Pancreatic Cancer

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12 December 2020

Automated registration of sequential breath-hold dynamic contrast-enhanced MR images: a comparison of three techniques

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12 December 2020

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

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12 December 2020

Gemcitabine versus gemcitabine plus dalteparin thromboprophylaxis in pancreatic cancer

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12 December 2020

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

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12 December 2020

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

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12 December 2020

Effective targeting of the tumor microenvironment for cancer therapy.

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12 December 2020

Modeling and predicting clinical efficacy for drugs targeting the tumor milieu

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12 December 2020

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

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12 December 2020

Venous thromboembolism risk in patients with cancer receiving chemotherapy: a real-world analysis

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12 December 2020

Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States

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12 December 2020

A Bayesian meta-analysis of multiple treatment comparisons of systemic regimens for advanced pancreatic cancer

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12 December 2020

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

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12 December 2020

Efficacy of Prophylactic Low-Molecular Weight Heparin for Ambulatory Patients With Advanced Pancreatic Cancer: Outcomes From the CONKO-004 Trial

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12 December 2020

10.1158/1078-0432.CCR-15-2010

Identifiers

DOI

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6 March 2020

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