Breaking free from the chains of pathway annotation: de novo pathway discovery for the analysis of disease processes. (Q46007895)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23215889 AND SRC:MED&resulttype=core&format=json

19 February 2020

title

Breaking free from the chains of pathway annotation: de novo pathway discovery for the analysis of disease processes (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23215889 AND SRC:MED&resulttype=core&format=json

19 February 2020

1

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19 February 2020

Thomas Schlitt

series ordinal

2

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19 February 2020

author name string

Benjamin Lehne

series ordinal

1

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18 December 2017

http://europepmc.org/abstract/MED/23215889

Thomas Schlitt

series ordinal

2

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18 December 2017

http://europepmc.org/abstract/MED/23215889

publication date

1 December 2012

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19 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23215889 AND SRC:MED&resulttype=core&format=json

19 February 2020

volume

13

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19 February 2020

issue

16

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19 February 2020

page(s)

1967-1978

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A Genetic Method for Determining the Order of Events in a Biological Pathway

19 February 2020

cites work

1 reference

Getting started in biological pathway construction and analysis.

21 January 2018

1 reference

Gene ontology: tool for the unification of biology

21 January 2018

1 reference

KEGG for linking genomes to life and the environment

21 January 2018

1 reference

Reactome: a database of reactions, pathways and biological processes

21 January 2018

1 reference

WikiPathways: building research communities on biological pathways

21 January 2018

1 reference

When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction

21 January 2018

1 reference

Molecular networks as sensors and drivers of common human diseases

21 January 2018

1 reference

g:Profiler--a web server for functional interpretation of gene lists (2011 update).

21 January 2018

1 reference

Statistical methods for pathway analysis of genome-wide data for association with complex genetic traits

21 January 2018

1 reference

Gene set enrichment analysis: performance evaluation and usage guidelines.

21 January 2018

1 reference

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 January 2018

1 reference

Analyzing gene expression data in terms of gene sets: methodological issues

21 January 2018

1 reference

GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies

21 January 2018

1 reference

Pathway-based approaches for analysis of genomewide association studies

21 January 2018

1 reference

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

Exome localization of complex disease association signals.

21 January 2018

1 reference

Linkage-disequilibrium-based binning affects the interpretation of GWASs

21 January 2018

1 reference

SCAN: SNP and copy number annotation

21 January 2018

1 reference

From SNPs to genes: disease association at the gene level

21 January 2018

1 reference

Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes

21 January 2018

1 reference

Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis

21 January 2018

1 reference

A versatile gene-based test for genome-wide association studies

21 January 2018

1 reference

Using genome-wide pathway analysis to unravel the etiology of complex diseases.

21 January 2018

1 reference

Strategies and issues in the detection of pathway enrichment in genome-wide association studies

21 January 2018

1 reference

Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach

21 January 2018

1 reference

Pathway analysis of seven common diseases assessed by genome-wide association

21 January 2018

1 reference

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease

21 January 2018

1 reference

Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder

21 January 2018

1 reference

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

21 January 2018

1 reference

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.

21 January 2018

1 reference

Fast identification of biological pathways associated with a quantitative trait using group lasso with overlaps

21 January 2018

1 reference

Analysing biological pathways in genome-wide association studies

21 January 2018

1 reference

Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study

21 January 2018

1 reference

Gene and pathway-based second-wave analysis of genome-wide association studies

21 January 2018

1 reference

A pathway analysis applied to Genetic Analysis Workshop 16 genome-wide rheumatoid arthritis data

21 January 2018

1 reference

Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission

21 January 2018

1 reference

Pathway analysis of genomic data: concepts, methods, and prospects for future development

21 January 2018

1 reference

Boosting signal-to-noise in complex biology: prior knowledge is power

21 January 2018

1 reference

NCBI GEO: mining tens of millions of expression profiles--database and tools update

21 January 2018

1 reference

ArrayExpress--a public repository for microarray gene expression data at the EBI

21 January 2018

1 reference

IntAct: an open source molecular interaction database

21 January 2018

1 reference

Development of human protein reference database as an initial platform for approaching systems biology in humans

21 January 2018

1 reference

APID: Agile Protein Interaction DataAnalyzer

21 January 2018

1 reference

Protein-protein interactions essentials: key concepts to building and analyzing interactome networks

21 January 2018

1 reference

Analyzing protein-protein interaction networks

21 January 2018

1 reference

Construction and analysis of protein-protein interaction networks

21 January 2018

1 reference

Shortest path analysis using partial correlations for classifying gene functions from gene expression data

21 January 2018

1 reference

Building and analysing genome-wide gene disruption networks.

21 January 2018

1 reference

From gene networks to gene function

21 January 2018

1 reference

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

21 January 2018

1 reference

Network medicine: a network-based approach to human disease

21 January 2018

1 reference

The modular nature of genetic diseases.

21 January 2018

1 reference

Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders

21 January 2018

1 reference

The human disease network

21 January 2018

1 reference

Predicting disease genes using protein-protein interactions.

21 January 2018

1 reference

Discovering disease-genes by topological features in human protein-protein interaction network

21 January 2018

1 reference

Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets

21 January 2018

1 reference

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

1 reference

Network properties of complex human disease genes identified through genome-wide association studies

21 January 2018

1 reference

Learning about gene regulatory networks from gene deletion experiments

21 January 2018

1 reference

Prioritizing candidate disease genes by network-based boosting of genome-wide association data.

21 January 2018

1 reference

Bayesian integration of networks without gold standards

21 January 2018

1 reference

Integrating physical and genetic maps: from genomes to interaction networks

21 January 2018

1 reference

Reverse-engineering human regulatory networks

21 January 2018

1 reference

Current approaches to gene regulatory network modelling

21 January 2018

1 reference

Mutual exclusivity analysis identifies oncogenic network modules

21 January 2018

1 reference

Is my network module preserved and reproducible?

21 January 2018

1 reference

An iterative network partition algorithm for accurate identification of dense network modules

21 January 2018

1 reference

Clustering by passing messages between data points

21 January 2018

1 reference

Massive human co-expression network and its medical applications

21 January 2018

1 reference

From sets to graphs: towards a realistic enrichment analysis of transcriptomic systems

21 January 2018

1 reference

A network of protein-protein interactions in yeast

21 January 2018

1 reference

An improved, bias-reduced probabilistic functional gene network of baker's yeast, Saccharomyces cerevisiae

21 January 2018

1 reference

Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes

21 January 2018

1 reference

Network-based classification of breast cancer metastasis

21 January 2018

1 reference

Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms

21 January 2018

1 reference

Classification of microarray data using gene networks

21 January 2018

1 reference

DEGAS: de novo discovery of dysregulated pathways in human diseases

21 January 2018

1 reference

Network-Induced Classification Kernels for Gene Expression Profile Analysis

21 January 2018

1 reference

A critical evaluation of network and pathway-based classifiers for outcome prediction in breast cancer

21 January 2018

1 reference

Discovery and scoring of protein interaction subnetworks discriminative of late stage human colon cancer

21 January 2018

1 reference

Integrative analysis for finding genes and networks involved in diabetes and other complex diseases

21 January 2018

1 reference

Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping data

21 January 2018

1 reference

The type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes

21 January 2018

1 reference

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

21 January 2018

1 reference

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology

21 January 2018

1 reference

dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks

21 January 2018

1 reference

A human phenome-interactome network of protein complexes implicated in genetic disorders

21 January 2018

1 reference

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions

21 January 2018

1 reference

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

21 January 2018

1 reference

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

Multiple common variants for celiac disease influencing immune gene expression

21 January 2018

1 reference

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

21 January 2018

1 reference

Comprehensive mapping of long-range interactions reveals folding principles of the human genome

21 January 2018

1 reference

Transcription factories: genetic programming in three dimensions

21 January 2018

1 reference

BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions

21 January 2018

1 reference

KEGG: kyoto encyclopedia of genes and genomes

21 January 2018

1 reference

Guilt-by-association goes global

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/PGS.12.170

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23215889 AND SRC:MED&resulttype=core&format=json

19 February 2020

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