Gene therapy of malignant glioma: recent advances in experimental and clinical studies (Q45890411)

17 December 2017

review article

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title

Gene therapy of malignant glioma: recent advances in experimental and clinical studies (English)

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17 December 2017

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M Sasaki

1

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17 December 2017

K H Plate

series ordinal

2

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17 December 2017

publication date

1 November 1998

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17 December 2017

published in

Annals of Oncology

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17 December 2017

volume

9

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17 December 2017

issue

11

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17 December 2017

page(s)

1155-1166

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17 December 2017

Long-term survival in patients with malignant astrocytoma

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Gene therapy for the treatment of malignant brain tumors with in vivo tumor transduction with the herpes simplex thymidine kinase gene/ganciclovir system

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Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors

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7 January 2021

Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line

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In vivo replication-deficient adenovirus vector-mediated transduction of the cytosine deaminase gene sensitizes glioma cells to 5-fluorocytosine

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Regression of Experimental Brain Tumors with 6-Thioxanthine andEscherichia coli gptGene Therapy

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Targeting of an inducible toxic phenotype in animal cells

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Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors

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7 January 2021

Bystander tumoricidal effect in the treatment of experimental brain tumors

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Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging

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In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

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The "bystander effect": association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice.

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Gene therapy of rat 9L gliosarcoma tumors by transduction with selectable genes does not require drug selection

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7 January 2021

The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats

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7 January 2021

Thymidine kinase-mediated killing of rat brain tumors

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7 January 2021

Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

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7 January 2021

Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells

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7 January 2021

In vivo transfer of the human interleukin-2 gene: negative tumoricidal results in experimental brain tumors.

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7 January 2021

Limited efficacy of the HSV-TK/GCV system for gene therapy of malignant gliomas and perspectives for the combined transduction of the interleukin-4 gene

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Selective enhancement of radiation response of herpes simplex virus thymidine kinase transduced 9L gliosarcoma cells in vitro and in vivo by antiviral agents

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7 January 2021

Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo

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Adenovirus-mediated gene therapy of experimental gliomas

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7 January 2021

Preclinical Testing of Recombinant Adenoviral Herpes Simplex Virus-Thymidine Kinase Gene Therapy for Central Nervous System Malignancies

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7 January 2021

Herpes simplex virus thymidine kinase gene therapy for rat malignant brain tumors

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7 January 2021

Preservation of the bystander cytocidal effect of irradiated herpes simplex virus thymidine kinase (HSV-tk) modified tumor cells

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7 January 2021

Curative potential of herpes simplex virus thymidine kinase gene transfer in rats with 9L gliosarcoma

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7 January 2021

Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells

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7 January 2021

Trans receptor inhibition of human glioblastoma cells by erbB family ectodomains.

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7 January 2021

Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants

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7 January 2021

Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1

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7 January 2021

Application of Antisense Ribonucleic Acid Complementary to O6-Methylguanine-deoxyribonucleic Acid Methyltransferase Messenger Ribonucleic Acid for Therapy of Malignant Gliomas

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7 January 2021

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7 January 2021

Transfection with bFGF sense and antisense cDNA resulting in modification of malignant glioma growth

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7 January 2021

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

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7 January 2021

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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7 January 2021

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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7 January 2021

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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7 January 2021

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

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7 January 2021

Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor

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7 January 2021

Gene therapy of malignant glioma via inhibition of tumor angiogenesis

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7 January 2021

Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma

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7 January 2021

Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

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7 January 2021

An experimental model of retrovirus gene therapy for malignant brain tumors

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7 January 2021

Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells

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7 January 2021

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells

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7 January 2021

Intrathecal gene therapy for the treatment of leptomeningeal carcinomatosis. GTI 0108. A phase I/II study

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7 January 2021

Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment.

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7 January 2021

Treatment of leptomeningeal metastases in a rat model using a recombinant adenovirus containing the HSV-tk gene

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7 January 2021

Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: a phase I trial.

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7 January 2021

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7 January 2021

Cellular and molecular neurosurgery: pathways from concept to reality--part II: vector systems and delivery methodologies for gene therapy of the central nervous system

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Isolation, Characterization, and use of Stem Cells from the CNS

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7 January 2021

Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells

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7 January 2021

Macrophages in experimental and human brain tumors. Part 1: Studies of the macrophage content of experimental rat brain tumors of varying immunogenicity

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7 January 2021

Identifiers

DOI

10.1023/A:1008488709359

1 reference

17 December 2017

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17 December 2017