A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A. (Q45864008)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28129116 AND SRC:MED&resulttype=core&format=json

9 April 2020

title

A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A (English)

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9 April 2020

13

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9 April 2020

Patrizia Perri

14

1 reference

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9 April 2020

Müjdat Zeybel

1

1 reference

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9 April 2020

Daniela Di Paolo

15

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9 April 2020

author name string

Saimir Luli

2

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9 April 2020

Laura Sabater

3

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9 April 2020

Timothy Hardy

4

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9 April 2020

Fiona Oakley

5

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9 April 2020

Jack Leslie

6

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9 April 2020

Agata Page

7

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9 April 2020

Eva Moran Salvador

8

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9 April 2020

Victoria Sharkey

9

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9 April 2020

Hidekazu Tsukamoto

10

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9 April 2020

David C K Chu

11

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9 April 2020

Uma Sharan Singh

12

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9 April 2020

Edgar J Mendivil

16

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Jelena Mann

17

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9 April 2020

Derek A Mann

18

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9 April 2020

publication date

4 January 2017

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9 April 2020

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9 April 2020

volume

25

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9 April 2020

issue

1

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9 April 2020

page(s)

218-231

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A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo

9 April 2020

cites work

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Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression

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Inhibition of DNA Methylation and Methyl-CpG-Binding Protein 2 Suppresses RPE Transdifferentiation: Relevance to Proliferative Vitreoretinopathy

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Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure

28 May 2018

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Diverse involvement of EZH2 in cancer epigenetics

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28 May 2018

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A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

28 May 2018

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28 May 2018

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28 May 2018

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A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic stellate cells

28 May 2018

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EZH2: biology, disease, and structure-based drug discovery

28 May 2018

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EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD.

28 May 2018

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Experimental liver fibrosis research: update on animal models, legal issues and translational aspects

28 May 2018

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Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.

28 May 2018

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IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts.

28 May 2018

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Enhanced anti-tumor and anti-angiogenic efficacy of a novel liposomal fenretinide on human neuroblastoma

28 May 2018

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Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

28 May 2018

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A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling

28 May 2018

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Epigenetic regulation of wound healing and fibrosis

28 May 2018

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

28 May 2018

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Oxymatrine liposome attenuates hepatic fibrosisviatargeting hepatic stellate cells

28 May 2018

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Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

28 May 2018

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Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation

28 May 2018

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Epigenetic cancer therapy: rationales, targets and drugs

28 May 2018

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Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma

28 May 2018

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Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK.

28 May 2018

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Essential role of MeCP2 in the regulation of myofibroblast differentiation during pulmonary fibrosis

28 May 2018

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Mechanisms of fibrosis: the role of the pericyte

28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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Generation of a monoclonal human single chain antibody fragment to hepatic stellate cells--a potential mechanism for targeting liver anti-fibrotic therapeutics.

28 May 2018

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Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis

28 May 2018

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The myofibroblast in wound healing and fibrocontractive diseases

28 May 2018

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Targeted delivery of antisense oligonucleotides in cancer

28 May 2018

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MeCP2 regulation of cardiac fibroblast proliferation and fibrosis by down-regulation of DUSP5.

28 May 2018

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Effects of interferon-gamma liposomes targeted to platelet-derived growth factor receptor–beta on hepatic fibrosis in rats

15 August 2018

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Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo

15 August 2018

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Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury.

15 August 2018

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Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone

15 August 2018

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15 August 2018

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Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis

15 August 2018

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Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis.

15 August 2018

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Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells

15 August 2018

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Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats

15 August 2018

1 reference

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A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture

15 August 2018

1 reference

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Fibrosis--A Common Pathway to Organ Injury and Failure

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28129116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Doxorubicin-loaded Fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28129116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.YMTHE.2016.10.004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28129116 AND SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28129116 AND SRC:MED&resulttype=core&format=json

9 April 2020

PubMed publication ID

28129116

1 reference