Ex vivo culture of chimeric antigen receptor T cells generates functional CD8 T cells with effector and central memory-like phenotype. (Q45858756)

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1 February 2020

title

Ex vivo culture of chimeric antigen receptor T cells generates functional CD8 T cells with effector and central memory-like phenotype (English)

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1

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Mark J. Smyth

8

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Michael H. Kershaw

10

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Phillip K. Darcy

11

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Simon Harrison

6

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Joseph A. Trapani

9

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author name string

A Shin

2

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K M Tainton

3

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P Guru

4

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H M Prince

5

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S Peinert

7

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D S Ritchie

12

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publication date

29 April 2010

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volume

17

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issue

9

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page(s)

1105-1116

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Cytotoxic T lymphocyte therapy for Epstein-Barr virus Hodgkin's disease

1 February 2020

cites work

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Adoptive immunotherapy for cancer: building on success

21 January 2018

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Fas-ligand-mediated lysis of erbB-2-expressing tumour cells by redirected cytotoxic T lymphocytes

21 January 2018

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Expression in cytotoxic T lymphocytes of a single-chain anti-carcinoembryonic antigen antibody. Redirected Fas ligand-mediated lysis of colon carcinoma

21 January 2018

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Rejection of Syngeneic Colon Carcinoma by CTLs Expressing Single-Chain Antibody Receptors Codelivering CD28 Costimulation

21 January 2018

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Adoptive transfer of gene-engineered CD4 helper T cells induces potent primary and secondary tumor rejection

21 January 2018

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Antitumor activity of dual-specific T cells and influenza virus

21 January 2018

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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8 T cells

21 January 2018

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Vaccine-stimulated, adoptively transferred CD8 T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction.

21 January 2018

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Central memory self/tumor-reactive CD8 T cells confer superior antitumor immunity compared with effector memory T cells

21 January 2018

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Induction of tolerance in CD8 T cells to a transgenic autoantigen expressed in the liver does not require cross-presentation

21 January 2018

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Interleukin-15 rescues tolerant CD8 T cells for use in adoptive immunotherapy of established tumors

21 January 2018

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

21 January 2018

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Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

21 January 2018

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Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression

21 January 2018

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Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy

21 January 2018

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

21 January 2018

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Gene-modified T cells for adoptive immunotherapy of renal cell cancer maintain transgene-specific immune functions in vivo

21 January 2018

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Adoptive transfer of chimeric FcepsilonRI gene-modified human T cells for cancer immunotherapy

21 January 2018

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Cancer regression in patients after transfer of genetically engineered lymphocytes

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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8 T cells

21 January 2018

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CD8 T-cell memory in tumor immunology and immunotherapy

21 January 2018

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Memory CD8 T cells vary in differentiation phenotype in different persistent virus infections

21 January 2018

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Understanding the generation and function of memory T cell subsets

21 January 2018

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Memory CD8 T-cell differentiation during viral infection

21 January 2018

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Chimeric NKG2D receptor-expressing T cells as an immunotherapy for multiple myeloma

21 January 2018

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Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

21 January 2018

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Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice

21 January 2018

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21 January 2018

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Supernatural T cells: genetic modification of T cells for cancer therapy

21 January 2018

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Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial.

21 January 2018

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Absence of retroviral vector-mediated transformation of gene-modified T cells after long-term engraftment in mice

21 January 2018

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Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Proliferation and differentiation potential of human CD8 memory T-cell subsets in response to antigen or homeostatic cytokines

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/GT.2010.59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20428216 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 February 2020

1002532847

0 references

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