Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. (Q45796087)

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20 January 2020

title

Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

20 January 2020

main subject

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author

Paolo Arosio

5

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20 January 2020

author name string

Suh Young Jeong

1

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20 January 2020

Khizr I Rathore

2

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20 January 2020

Katrin Schulz

3

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20 January 2020

Prem Ponka

4

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20 January 2020

Samuel David

6

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20 January 2020

language of work or name

English

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publication date

1 January 2009

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20 January 2020

published in

Journal of Neuroscience

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20 January 2020

volume

29

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20 January 2020

issue

3

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20 January 2020

page(s)

610-619

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describes a project that uses

20 January 2020

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

12 December 2020

The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins

1 reference

12 December 2020

Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2.

1 reference

12 December 2020

A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins

1 reference

12 December 2020

Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress

1 reference

12 December 2020

Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut

1 reference

12 December 2020

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

12 December 2020

Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.

1 reference

12 December 2020

Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.

1 reference

12 December 2020

Tumor necrosis factor and motoneuronal degeneration: an open problem.

1 reference

12 December 2020

Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading

1 reference

12 December 2020

Peptidylprolyl isomerase A (PPIA) as a preferred internal control over GAPDH and beta-actin in quantitative RNA analyses

1 reference

12 December 2020

Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.

1 reference

12 December 2020

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

The efficacy of trientine or ascorbate alone compared to that of the combined treatment with these two agents in familial amyotrophic lateral sclerosis model mice

1 reference

12 December 2020

Efficient three-drug cocktail for disease induced by mutant superoxide dismutase

1 reference

12 December 2020

Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system

1 reference

12 December 2020

Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals

1 reference

12 December 2020

Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis

1 reference

12 December 2020

A study of potential toxic effects after repeated 10-week administration of a new iron chelator--salicylaldehyde isonicotinoyl hydrazone (SIH) to rabbits.

1 reference

12 December 2020

Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier

1 reference

12 December 2020

Iron metabolism and the IRE/IRP regulatory system: an update

1 reference

12 December 2020

Hereditary causes of disturbed iron homeostasis in the central nervous system

1 reference

12 December 2020

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

1 reference

12 December 2020

Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells

1 reference

12 December 2020

Protein aggregation and neurodegenerative disease

1 reference

12 December 2020

Transferrin receptor 1 mRNA is downregulated in placenta of hepcidin transgenic embryos.

1 reference

12 December 2020

Iron, brain ageing and neurodegenerative disorders

1 reference

12 December 2020

Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.

1 reference

12 December 2020

Iron trafficking in the mitochondrion: novel pathways revealed by disease.

1 reference

12 December 2020

Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis

1 reference

12 December 2020

Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism

1 reference

12 December 2020

Mitochondrial dysfunction and amyotrophic lateral sclerosis

1 reference

12 December 2020

Cellular regulation and molecular interactions of the ferritins.

1 reference

12 December 2020

Transgenic mouse models of amyotrophic lateral sclerosis

1 reference

12 December 2020

Superoxide dismutase 1 modulates expression of transferrin receptor.

1 reference

12 December 2020

Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target

1 reference

12 December 2020

Mechanisms of iron-sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes

1 reference

12 December 2020

NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1.

1 reference

12 December 2020

Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide

1 reference

12 December 2020

Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials.

1 reference

12 December 2020

1 reference

12 December 2020

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

12 December 2020

Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis

1 reference

12 December 2020

Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels

1 reference

12 December 2020

Molecular regulation of hepatic expression of iron regulatory hormone hepcidin

1 reference

12 December 2020

The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Lipopolysaccharide induces a significant increase in expression of iron regulatory hormone hepcidin in the cortex and substantia nigra in rat brain

1 reference

12 December 2020

Iron-independent induction of ferritin H chain by tumor necrosis factor

1 reference

12 December 2020

Interleukin 1 induces ferritin heavy chain in human muscle cells

1 reference

12 December 2020

The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene

1 reference

12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

12 December 2020

Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha

1 reference

12 December 2020

Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging

1 reference

12 December 2020

The role of O2.- in the production of HO.: in vitro and in vivo

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: a preliminary study

1 reference

12 December 2020

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

1 reference

12 December 2020

Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis

1 reference

12 December 2020

Low intensity areas observed on T2-weighted magnetic resonance imaging of the cerebral cortex in various neurological diseases.

1 reference

12 December 2020

Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis.

1 reference

12 December 2020

The Copper Chelator d‐Penicillamine Delays Onset of Disease and Extends Survival in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis

1 reference

12 December 2020

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

1 reference

12 December 2020

Neurofilaments and Orthograde Transport Are Reduced in Ventral Root Axons of Transgenic Mice that Express Human SOD1 with a G93A Mutation

1 reference

12 December 2020

Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1

1 reference

12 December 2020

Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease

1 reference

12 December 2020

Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant

1 reference

12 December 2020

10.1523/JNEUROSCI.5443-08.2009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19158288 AND SRC:MED&resulttype=core&format=json

20 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19158288 AND SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

19158288

1 reference