Epstein-Barr virus-encoded EBNA-5 forms trimolecular protein complexes with MDM2 and p53 and inhibits the transactivating function of p53. (Q45375969)

13 December 2017

title

Epstein-Barr virus-encoded EBNA-5 forms trimolecular protein complexes with MDM2 and p53 and inhibits the transactivating function of p53. (English)

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13 December 2017

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1

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13 December 2017

Mariya Yurchenko

2

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Laszlo Szekely

object named as

Laszlo Szekely

5

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Boris Snopok

object named as

Boris Snopok

4

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Aaron Ciechanover

7

object named as

Aaron Ciechanover

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13 December 2017

author name string

Surya Pavan Yenamandra

3

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13 December 2017

Beatrice Bercovich

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13 December 2017

George Klein

8

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13 December 2017

language of work or name

English

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publication date

1 February 2011

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International Journal of Cancer

13 December 2017

published in

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13 December 2017

volume

128

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13 December 2017

issue

4

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13 December 2017

page(s)

817-825

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The p53 pathway: positive and negative feedback loops

13 December 2017

cites work

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Association of human papillomavirus types 16 and 18 E6 proteins with p53.

21 January 2018

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Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

21 January 2018

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Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

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The tumor suppressor p53 and the oncoprotein simian virus 40 T antigen bind to overlapping domains on the MDM2 protein

21 January 2018

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ORF73 of herpesvirus saimiri, a viral homolog of Kaposi's sarcoma-associated herpesvirus, modulates the two cellular tumor suppressor proteins p53 and pRb.

21 January 2018

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Epstein-Barr virus infection and mitogen stimulation of normal B cells induces wild-type p53 without subsequent growth arrest or apoptosis

21 January 2018

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EBV-encoded EBNA-5 associates with P14ARF in extranucleolar inclusions and prolongs the survival of P14ARF-expressing cells

21 January 2018

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PRIMA-1MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein.

21 January 2018

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SPR-based immunocapture approach to creating an interfacial sensing architecture: Mapping of the MRS18-2 binding site on retinoblastoma protein

21 January 2018

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Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation

21 January 2018

1 reference

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

Epstein-Barr virus EBNA3 proteins bind to the C8/alpha7 subunit of the 20S proteasome and are degraded by 20S proteasomes in vitro, but are very stable in latently infected B cells

21 January 2018

1 reference

Autorepression of Epstein-Barr virus nuclear antigen 1 expression by inhibition of pre-mRNA processing

21 January 2018

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Structure and function of the Epstein-Barr virus transcription factor, EBNA 3C.

21 January 2018

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Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation.

21 January 2018

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p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y

21 January 2018

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Cell cycle arrest following exposure of EBV-immortalised B-cells to gamma irradiation correlates with inhibition of cdk2 activity

21 January 2018

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The ubiquitin-proteasome pathway: on protein death and cell life

21 January 2018

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.

21 January 2018

1 reference

Transcriptional regulation by p53: one protein, many possibilities

21 January 2018

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P53 promoter selection: choosing between life and death

21 January 2018

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Epstein-Barr virus selectively deregulates DNA damage responses in normal B cells but has no detectable effect on regulation of the tumor suppressor p53.

21 January 2018

1 reference

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

21 January 2018

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

The specific activation of gadd45 following UVB radiation requires the POU family gene product N-oct3 in human melanoma cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

p53 inhibition by the LANA protein of KSHV protects against cell death

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

Specific interaction of the SV40 T antigen-cellular p53 protein complex with SV40 DNA

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

Study on the Spatial Architecture of p53, MDM2, and p14ARF Containing Complexes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/IJC.25414

Identifiers

DOI

10.1002/IJC.25414

1 reference

13 December 2017

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