Emergence of simian immunodeficiency virus-specific cytotoxic CD4 T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency vi (Q45373800)

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scientific article published on 11 August 2010

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English	Emergence of simian immunodeficiency virus-specific cytotoxic CD4 T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency vi	scientific article published on 11 August 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Emergence of simian immunodeficiency virus-specific cytotoxic CD4 T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency vi (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Simian immunodeficiency virus

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attenuated vaccine

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based on heuristic

inferred from title

David C. Montefiori

6

object named as

David C Montefiori

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

author name string

Agneta von Gegerfelt

1

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Europe PubMed Central

PubMed publication ID

13 December 2017

Antonio Valentin

2

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Candido Alicea

3

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Koen K A Van Rompay

4

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Marta L Marthas

5

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

George N Pavlakis

7

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Barbara K Felber

8

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Europe PubMed Central

PubMed publication ID

13 December 2017

language of work or name

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publication date

11 August 2010

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Europe PubMed Central

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13 December 2017

Journal of Immunology

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Europe PubMed Central

PubMed publication ID

13 December 2017

185

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Europe PubMed Central

PubMed publication ID

13 December 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

3348-3358

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

CD4 T cells mediate killing during persistent gammaherpesvirus 68 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

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Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replacement of posttranscriptional regulation in SIVmac239 generated a Rev-independent infectious virus able to propagate in rhesus peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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Perforin-dependent cytotoxic activity and lymphokine secretion by CD4 T cells are regulated by CD8 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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Dramatic rise in plasma viremia after CD8( ) T cell depletion in simian immunodeficiency virus-infected macaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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Profound CD4 /CCR5 T cell expansion is induced by CD8 lymphocyte depletion but does not account for accelerated SIV pathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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Novel, live attenuated simian immunodeficiency virus constructs containing major deletions in leader RNA sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

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Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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The posttranscriptional control element of the simian retrovirus type 1 forms an extensive RNA secondary structure necessary for its function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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Role of CD8 cells in controlling replication of nonpathogenic Simian Immunodeficiency Virus SIVmac1A11.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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HIV vaccine design: insights from live attenuated SIV vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long lasting control and lack of pathogenicity of the attenuated Rev-independent SIV in rhesus macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of circulating antigen-specific CD4 T lymphocytes with a CCR5 , cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction and in vitro properties of a series of attenuated simian immunodeficiency viruses with all accessory genes deleted

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

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Administration of an Anti-CD8 Monoclonal Antibody Interferes with the Clearance of Chimeric Simian/Human Immunodeficiency Virus during Primary Infections of Rhesus Macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of CD8 T cells to containment of viral replication and emergence of mutations in Mamu-A*01-restricted epitopes in Simian immunodeficiency virus-infected rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Highly Attenuated Mutants of Simian Immunodeficiency Virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nonhuman primate model for the selective elimination of CD8 lymphocytes using a mouse-human chimeric monoclonal antibody.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo CD8 T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live, attenuated simian immunodeficiency virus vaccines elicit potent resistance against a challenge with a human immunodeficiency virus type 1 chimeric virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased loss of CCR5 CD45RA- CD4 T cells in CD8 lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CD4( ) CTLs ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8 cell depletion amplifies the acute retroviral syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an RNA sequence within an intracisternal-A particle element able to replace Rev-mediated posttranscriptional regulation of human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct killing of Epstein-Barr virus (EBV)-infected B cells by CD4 T cells directed against the EBV lytic protein BHRF1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranscriptional control of HIV-1 and other retroviruses and its practical applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How do cytotoxic lymphocytes kill their targets?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of viremia in simian immunodeficiency virus infection by CD8 lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of CD8 T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live, attenuated simian immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8 lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection by live, attenuated simian immunodeficiency virus against heterologous challenge.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of in vivo CD8( ) T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma SIV RNA Viral Load Determination by Real-Time Quantification of Product Generation in Reverse Transcriptase-Polymerase Chain Reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new reagent for the induction of T-cell depletion, anti-CD3-CRM9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of CD8 lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human immunodeficiency virus replication in acutely infected CD4 cells by CD8 cells involves a noncytotoxic mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquisition of direct antiviral effector functions by CMV-specific CD4 T lymphocytes with cellular maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutralizing antibodies in sera from macaques immunized with attenuated simian immunodeficiency virus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live attenuated HIV vaccines: pitfalls and prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD8( ) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a population of CD4 CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal natural killer cells produce chemokines and suppress HIV replication in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of simian immunodeficiency virus (SIV) replication by CD8( ) T lymphocytes from macaques immunized with live attenuated SIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of protection induced by attenuated simian immunodeficiency virus. IV. Protection against challenge with virus grown in autologous simian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8 cell depletion of SHIV89.6P-infected macaques induces CD4 T cell proliferation that contributes to increased viral loads

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: MHC class II-restricted killing in vivo during viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent infection of rhesus macaques by the rev-independent Nef(-) simian immunodeficiency virus SIVmac239: replication kinetics and genomic stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rev-independent simian immunodeficiency virus strains are nonpathogenic in neonatal macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural killer cells from human immunodeficiency virus (HIV)-infected individuals are an important source of CC-chemokines and suppress HIV-1 entry and replication in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of human immunodeficiency virus type 1 replication by a soluble factor produced by CD8 lymphocytes from HIV-2-infected baboons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1000572

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

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