Entrapment of small molecules and nucleic acid-based drugs in liposomes (Q45274488)

11 December 2017

title

Entrapment of small molecules and nucleic acid-based drugs in liposomes (English)

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11 December 2017

2

Pieter R Cullis

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11 December 2017

David B Fenske

1

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11 December 2017

language of work or name

English

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publication date

1 January 2005

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11 December 2017

published in

Methods in Enzymology

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11 December 2017

volume

391

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11 December 2017

page(s)

7-40

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Controlled destabilization of a liposomal drug delivery system enhances mitoxantrone antitumor activity

11 December 2017

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Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

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Improved efficacy of ciprofloxacin administered in polyethylene glycol-coated liposomes for treatment of Klebsiella pneumoniae pneumonia in rats

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Dopamine accumulation in large unilamellar vesicle systems induced by transmembrane ion gradients

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Membrane models with phospholipids

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Single bilayer liposomes prepared without sonication

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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Optimization of the retention properties of vincristine in liposomal systems

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Phase I study of Doxil and vinorelbine in metastatic breast cancer

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The clinical utility of liposomal doxorubicin in recurrent ovarian cancer

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Plasma clearance, biodistribution and therapeutic properties of mitoxantrone encapsulated in conventional and sterically stabilized liposomes after intravenous administration in BDF1 mice

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Loading of doxorubicin into liposomes by forming Mn2 -drug complexes

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Recent advances in liposomal drug-delivery systems

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Polyethylene glycol-liposomal doxorubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of AIDS-related Kaposi's sarcoma

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Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles

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Stabilized plasmid-lipid particles: a systemic gene therapy vector

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Ionophore-mediated uptake of ciprofloxacin and vincristine into large unilamellar vesicles exhibiting transmembrane ion gradients

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Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors

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Phase I study of liposomal vincristine

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Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma

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An improved method of encapsulation of doxorubicin in liposomes: pharmacological, toxicological and therapeutic evaluation

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Phase II study of liposomal doxorubicin in platinum- and paclitaxel-refractory epithelial ovarian cancer.

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Lipid peroxidation and possible hydroxyl radical formation stimulated by the self-reduction of a doxorubicin-iron (III) complex

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7 January 2021

Free radical damage to deoxyribose by anthracycline, aureolic acid and aminoquinone antitumour antibiotics. An essential requirement for iron, semiquinones and hydrogen peroxide

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7 January 2021

Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases

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7 January 2021

Accumulation of doxorubicin and other lipophilic amines into large unilamellar vesicles in response to transmembrane pH gradients

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7 January 2021

The interaction of the cardioprotective agent ICRF-187 [ )-1,2-bis(3,5-dioxopiperazinyl-1-yL)propane); its hydrolysis product (ICRF-198); and other chelating agents with the Fe(III) and Cu(II) complexes of adriamycin

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7 January 2021

Self-reduction of the iron(III)-doxorubicin complex

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7 January 2021

The Adriamycin (doxorubicin)-induced inactivation of cytochrome c oxidase depends on the presence of iron or copper

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7 January 2021

Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential

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7 January 2021

Programmable fusogenic vesicles for intracellular delivery of antisense oligodeoxynucleotides: enhanced cellular uptake and biological effects

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7 January 2021

Studies on phosphatidylcholine vesicles. Formation and physical characteristics

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7 January 2021

Phase II study of liposomal doxorubicin in advanced gynecologic cancers

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7 January 2021

Randomised phase II trial of pegylated liposomal doxorubicin (DOXIL/CAELYX) versus doxorubicin in the treatment of advanced or metastatic soft tissue sarcoma: a study by the EORTC Soft Tissue and Bone Sarcoma Group

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7 January 2021

Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery

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7 January 2021

Gelation of liposome interior. A novel method for drug encapsulation

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7 January 2021

Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient

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7 January 2021

The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey

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Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients

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Lipid-based systems for the intracellular delivery of genetic drugs

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7 January 2021

Anomalous solubility behavior of the antibiotic ciprofloxacin encapsulated in liposomes: a 1H-NMR study

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7 January 2021

Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes

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7 January 2021

Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient

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7 January 2021

Vesicles of variable sizes produced by a rapid extrusion procedure

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7 January 2021

Comparison of free and liposome encapsulated doxorubicin tumor drug uptake and antitumor efficacy in the SC115 murine mammary tumor

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7 January 2021

Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia

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7 January 2021

Liposomal vincristine for the treatment of human acute lymphoblastic leukaemia in severe combined immunodeficient (SCID) mice

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7 January 2021

Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside

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7 January 2021

Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties

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7 January 2021

Liposomal encapsulated anthracyclines: new therapeutic horizons

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7 January 2021

Hydroxyl radical production and DNA damage induced by anthracycline-iron complex

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomized phase III clinical trial.

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Liposomal daunorubicin:in vitro andin vivo efficacy in multiple myeloma

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

64 The measurement of membrane potential and ΔpH in cells, organelles, and vesicles

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7 January 2021

Encapsulation of plasmid DNA in stabilized plasmid-lipid particles composed of different cationic lipid concentration for optimal transfection activity

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Lipid-based formulations of antisense oligonucleotides for systemic delivery applications

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Phase II study of liposomal doxorubicin in patients with advanced colorectal cancer

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

A new liposomal formulation for antisense oligodeoxynucleotides with small size, high incorporation efficiency and good stability

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

A novel, long-circulating, and functional liposomal formulation of antisense oligodeoxynucleotides targeted against MDR1.

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

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7 January 2021

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation

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7 January 2021

Stabilized plasmid-lipid particles for systemic gene therapy

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Antitumor activity of vincristine encapsulated in glucuronide-modified long-circulating liposomes in mice bearing Meth A sarcoma

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7 January 2021

Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol

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7 January 2021

Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models

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7 January 2021

Preclinical pharmacology, toxicology and efficacy of sphingomyelin/cholesterol liposomal vincristine for therapeutic treatment of cancer

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7 January 2021

Antibacterial Efficacy against an In Vivo Salmonella typhimurium Infection Model and Pharmacokinetics of a Liposomal Ciprofloxacin Formulation

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Stabilized plasmid-lipid particles: construction and characterization

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Ionophore-mediated loading of Ca2 into large unilamellar vesicles in response to transmembrane pH gradients

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA.

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Sterically stabilized liposomes: physical and biological properties

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

Liposomes: preparation, characterization, and preservation

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https://api.crossref.org/works/10.1016/S0076-6879(05)91001-X

7 January 2021

10.1016/S0076-6879(05)91001-X

Identifiers

DOI

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11 December 2017

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