Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis. (Q45138742)

PubMed publication ID

15525785

9 December 2017

title

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis (English)

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12 May 2020

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Daniel A Linseman

1

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12 May 2020

Brent D Butts

2

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12 May 2020

Thomas A Precht

3

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12 May 2020

Reid A Phelps

4

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12 May 2020

Shoshona S Le

5

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12 May 2020

Tracey A Laessig

6

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Ron J Bouchard

7

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Maria L Florez-McClure

8

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12 May 2020

Kim A Heidenreich

9

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12 May 2020

language of work or name

English

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publication date

1 November 2004

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PubMed publication ID

15525785

9 December 2017

published in

Journal of Neuroscience

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12 May 2020

volume

24

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12 May 2020

issue

44

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12 May 2020

page(s)

9993-10002

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

12 May 2020

cites work

1 reference

12 December 2020

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

12 December 2020

Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons

1 reference

12 December 2020

Optimized protocol for biolistic transfection of brain slices and dissociated cultured neurons with a hand-held gene gun

1 reference

12 December 2020

Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal

1 reference

12 December 2020

JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system

1 reference

12 December 2020

Characterization of Bax-sigma, a cell death-inducing isoform of Bax

1 reference

12 December 2020

Bax inactivation in lurcher mutants rescues cerebellar granule cells but not purkinje cells or inferior olivary neurons

1 reference

12 December 2020

Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta.

1 reference

12 December 2020

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

1 reference

12 December 2020

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

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12 December 2020

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

12 December 2020

Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.

1 reference

12 December 2020

PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

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12 December 2020

The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

1 reference

12 December 2020

The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria

1 reference

12 December 2020

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

12 December 2020

Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors

1 reference

12 December 2020

The GSK3 beta signaling cascade and neurodegenerative disease.

1 reference

12 December 2020

Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons.

1 reference

12 December 2020

14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax

1 reference

12 December 2020

14-3-3 connects glycogen synthase kinase-3 beta to tau within a brain microtubule-associated tau phosphorylation complex

1 reference

12 December 2020

Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3

1 reference

12 December 2020

Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

1 reference

12 December 2020

GSK-3: tricks of the trade for a multi-tasking kinase

1 reference

12 December 2020

Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3.

1 reference

12 December 2020

Targeting programmed cell death in neurodegenerative diseases

1 reference

12 December 2020

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

1 reference

12 December 2020

A myocyte enhancer factor 2D (MEF2D) kinase activated during neuronal apoptosis is a novel target inhibited by lithium

1 reference

12 December 2020

Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53

1 reference

12 December 2020

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

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12 December 2020

Conformational control of Bax localization and apoptotic activity by Pro168.

1 reference

12 December 2020

Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3

1 reference

12 December 2020

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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12 December 2020

Nonionic detergents induce dimerization among members of the Bcl-2 family

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12 December 2020

Movement of Bax from the Cytosol to Mitochondria during Apoptosis

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12 December 2020

Role of MAP kinase in neurons

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12 December 2020

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

1 reference

12 December 2020

10.1523/JNEUROSCI.2057-04.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730230&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730230&resulttype=core&format=json

12 May 2020

PubMed publication ID

15525785

1 reference