T0901317 is a dual LXR/FXR agonist (Q45089589)

9 December 2017

title

T0901317 is a dual LXR/FXR agonist (English)

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9 December 2017

Keith A Houck

1

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9 December 2017

Kristen M Borchert

2

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9 December 2017

Christopher D Hepler

3

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9 December 2017

Jeffrey S Thomas

4

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9 December 2017

Kelli S Bramlett

5

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9 December 2017

Laura F Michael

6

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9 December 2017

Thomas P Burris

7

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9 December 2017

publication date

1 September 2004

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Molecular Genetics and Metabolism

9 December 2017

published in

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9 December 2017

volume

83

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9 December 2017

issue

1-2

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9 December 2017

page(s)

184-187

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Orphan nuclear receptor modulators

9 December 2017

cites work

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Identification of a nuclear receptor that is activated by farnesol metabolites

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A natural product ligand of the oxysterol receptor, liver X receptor.

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A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor.

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Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

7 January 2021

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

7 January 2021

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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LXR, a nuclear receptor that defines a distinct retinoid response pathway

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

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Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

7 January 2021

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Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

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7 January 2021

Identifiers

DOI

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9 December 2017

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