Systemic mastocytosis in adults: 2011 update on diagnosis, risk stratification, and management (Q45058347)

9 December 2017

title

Systemic mastocytosis in adults: 2011 update on diagnosis, risk stratification, and management (English)

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9 December 2017

main subject

systemic mastocytosis

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Animesh Pardanani

1

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9 December 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21442641

28 November 2024

publication date

1 April 2011

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9 December 2017

April 2011

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21442641

full work available at URL

28 November 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002/ajh.21982

1 reference

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajh.21982

28 November 2024

1 reference

American Journal of Hematology

28 November 2024

published in

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9 December 2017

volume

86

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9 December 2017

issue

4

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9 December 2017

page(s)

362-371

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Bone marrow findings in systemic mastocytosis

9 December 2017

cites work

1 reference

Bone marrow mast cell morphologic features and hematopoietic dyspoiesis in systemic mast cell disease

21 January 2018

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Pediatric-onset mastocytosis: a long term clinical follow-up and correlation with bone marrow histopathology

21 January 2018

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Urticaria pigmentosa: a review of 67 pediatric cases

21 January 2018

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Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors

21 January 2018

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A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome

21 January 2018

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Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness

21 January 2018

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Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome

21 January 2018

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FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia

21 January 2018

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Imatinib for systemic mast-cell disease

21 January 2018

1 reference

CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy

21 January 2018

1 reference

Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene.

21 January 2018

1 reference

Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: a histopathological challenge

21 January 2018

1 reference

Detection of c-kit point mutation Asp-816 --> Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia.

21 January 2018

1 reference

Significance of systemic mast cell disease with associated hematologic disorders

21 January 2018

1 reference

Prognostically relevant breakdown of 123 patients with systemic mastocytosis associated with other myeloid malignancies

21 January 2018

1 reference

Demonstration that mast cells, T cells, and B cells bearing the activating kit mutation D816V occur in clusters within the marrow of patients with mastocytosis

21 January 2018

1 reference

KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation

21 January 2018

1 reference

Identification of activating c-kit mutations in adult-, but not in childhood-onset indolent mastocytosis: a possible explanation for divergent clinical behavior

21 January 2018

1 reference

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

21 January 2018

1 reference

One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes

21 January 2018

1 reference

Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis

21 January 2018

1 reference

Mast cell disease associated with acute myeloid leukemia: detection of a new c-kit mutation Asp816His

21 January 2018

1 reference

Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations.

21 January 2018

1 reference

c-kit Mutations in patients with childhood-onset mastocytosis and genotype-phenotype correlation

21 January 2018

1 reference

KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors

21 January 2018

1 reference

Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia

21 January 2018

1 reference

Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis

21 January 2018

1 reference

A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy

21 January 2018

1 reference

A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib

21 January 2018

1 reference

A germline mutation in KIT in familial diffuse cutaneous mastocytosis

21 January 2018

1 reference

Mastocytosis in mice expressing human Kit receptor with the activating Asp816Val mutation

21 January 2018

1 reference

Mast cell hyperplasia, B-cell malignancy, and intestinal inflammation in mice with conditional expression of a constitutively active kit.

21 January 2018

1 reference

Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates

21 January 2018

1 reference

Expression of a constitutively active mutant of M-Ras in normal bone marrow is sufficient for induction of a malignant mastocytosis/mast cell leukemia, distinct from the histiocytosis/monocytic leukemia induced by expression of activated H-Ras.

21 January 2018

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Histopathological and immunohistochemical aspects of mastocytosis.

21 January 2018

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CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens.

21 January 2018

1 reference

Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: evidence for expression of CD2, CD117/Kit, and bcl-x(L).

21 January 2018

1 reference

Flow cytometric analysis of normal and neoplastic mast cells: role in diagnosis and follow-up of mast cell disease

21 January 2018

1 reference

Bone marrow mast cell immunophenotyping in adults with mast cell disease: a prospective study of 33 patients

21 January 2018

1 reference

Mast cells as "tunable" effector and immunoregulatory cells: recent advances.

21 January 2018

1 reference

Molecular diagnosis of mast cell disorders: a paper from the 2005 William Beaumont Hospital Symposium on Molecular Pathology

21 January 2018

1 reference

Variable presence of KITD816V in clonal haematological non-mast cell lineage diseases associated with systemic mastocytosis (SM-AHNMD).

21 January 2018

1 reference

Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients.

21 January 2018

1 reference

Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria

21 January 2018

1 reference

Proposal for a revised classification of systemic mastocytosis.

21 January 2018

1 reference

Response of severe systemic mastocytosis to interferon alpha

21 January 2018

1 reference

Successful treatment of systemic mastocytosis with high-dose interferon-alfa: long-term follow-up of a case

21 January 2018

1 reference

Response to therapy with interferon alpha-2b and prednisolone in aggressive systemic mastocytosis: report of five cases and review of the literature.

21 January 2018

1 reference

Management of patients with systemic mastocytosis: review of M. D. Anderson Cancer Center experience

21 January 2018

1 reference

Cytoreductive therapy in 108 adults with systemic mastocytosis: Outcome analysis and response prediction during treatment with interferon-alpha, hydroxyurea, imatinib mesylate or 2-chlorodeoxyadenosine

21 January 2018

1 reference

Interest of interferon alpha in systemic mastocytosis. The French experience and review of the literature

21 January 2018

1 reference

In vitro and in vivo growth-inhibitory effects of cladribine on neoplastic mast cells exhibiting the imatinib-resistant KIT mutation D816V.

21 January 2018

1 reference

PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects

21 January 2018

1 reference

Cladribine therapy in a patient with an aleukemic subvariant of mast cell leukemia

21 January 2018

1 reference

Treatment of systemic mast-cell disease with cladribine

21 January 2018

1 reference

Cladribine therapy for systemic mastocytosis.

21 January 2018

1 reference

Treatment of systemic mast cell disease with 2-chlorodeoxyadenosine

21 January 2018

1 reference

Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms

21 January 2018

1 reference

Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit

21 January 2018

1 reference

The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations

21 January 2018

1 reference

Imatinib mesylate in the treatment of systemic mastocytosis: a phase II trial

21 January 2018

1 reference

Phase II study of imatinib mesylate as therapy for patients with systemic mastocytosis

21 January 2018

1 reference

Advanced mast cell disease: an Italian Hematological Multicenter experience

21 January 2018

1 reference

Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies

21 January 2018

1 reference

Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis

21 January 2018

1 reference

Synergistic growth-inhibitory effects of two tyrosine kinase inhibitors, dasatinib and PKC412, on neoplastic mast cells expressing the D816V-mutated oncogenic variant of KIT.

21 January 2018

1 reference

Treatment responses to cladribine and dasatinib in rapidly progressing aggressive mastocytosis.

21 January 2018

1 reference

Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V.

21 January 2018

1 reference

Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis

21 January 2018

1 reference

Dasatinib therapy for systemic mastocytosis: four cases

21 January 2018

1 reference

Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.

21 January 2018

1 reference

Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.

21 January 2018

1 reference

Systemic mastocytosis. Extracutaneous manifestations.

21 January 2018

2

1 reference

The natural course of urticaria pigmentosa. Analysis and follow-up of 112 cases

28 November 2024

5

1 reference

Imatinib mesylate responsiveness in aggressive systemic mastocytosis: novel association with a platelet derived growth factor receptor beta mutation

28 November 2024

17

1 reference

Eosinophils are derived from the neoplastic clone in patients with systemic mastocytosis and eosinophilia

28 November 2024

23

1 reference

KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients

28 November 2024

30

1 reference

In VivoDifferentiation of Mast Cells from Acute Myeloid Leukemia Blasts Carrying a Novel Activating Ligand-Independent C-kit Mutation

28 November 2024

34

1 reference

A new c-kit mutation in a case of aggressive mast cell disease

28 November 2024

37

1 reference

C-kit Asp-816-Val mutation analysis in patients with mastocytosis

28 November 2024

40

1 reference

c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia

28 November 2024

41

1 reference

Diagnostic value of immunostaining for tryptase in patients with mastocytosis

28 November 2024

53

1 reference

Elevated tryptase levels selectively cluster in myeloid neoplasms: a novel diagnostic approach and screen marker in clinical haematology

28 November 2024

60

1 reference

WHO subvariants of indolent mastocytosis: clinical details and prognostic evaluation in 159 consecutive adults

28 November 2024

61

1 reference

Evidence for the involvement of a hematopoietic progenitor cell in systemic mastocytosis from single-cell analysis of mutations in the c-kit gene

28 November 2024

63

1 reference

A pilot study of nonmyeloablative allogeneic hematopoietic stem cell transplant for advanced systemic mastocytosis

28 November 2024

67

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Response to interferon alfa-2b in a patient with systemic mastocytosis

28 November 2024

70

1 reference

Treatment of urticaria pigmentosa using interferon alpha.

28 November 2024

73

1 reference

Severe osteoporosis due to systemic mast cell disease: successful treatment with interferon alpha-2B

28 November 2024

74

1 reference

IFNalpha treatment in systemic mastocytosis

28 November 2024

75

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Successful treatment of osteoporosis in systemic mastocytosis with interferon alpha-2b

28 November 2024

77

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Long-term effect of interferon alpha treatment in mastocytosis

28 November 2024

79

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Systemic mastocytosis associated with chronic myelomonocytic leukemia: clinical features and response to interferon alfa therapy

28 November 2024

80

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Treatment of three patients with systemic mastocytosis with interferon alpha-2b

28 November 2024

81

1 reference

[Interferon alpha and pamidronate: a useful combination in the treatment of osteoporosis and systemic mastocytosis]

28 November 2024

82

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Interferon treatment of patients with chronic urticaria and mastocytosis

28 November 2024

83

1 reference

lnterferon-α in combination with corticosteroids improves systemic mast cell disease

28 November 2024

85

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Long-term effect of interferon alpha treatment in mastocytosis

28 November 2024

86

1 reference

Long Term Efficacy and Safety of Cladribine In Adult Systemic mastocytosis: a French Multicenter Study of 44 Patients

28 November 2024

95

1 reference

Juxtamembrane-type c-kit gene mutation found in aggressive systemic mastocytosis induces imatinib-resistant constitutive KIT activation

28 November 2024

99

1 reference

28 November 2024

Identifiers

DOI

10.1002/AJH.21982

1 reference

9 December 2017

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