Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons (Q45004321)

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English	Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 December 2017

Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons (English)

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Europe PubMed Central

PubMed publication ID

8 December 2017

apoptotic process

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author name string

Kanai H

1

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Europe PubMed Central

PubMed publication ID

8 December 2017

Sawa A

2

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Europe PubMed Central

PubMed publication ID

8 December 2017

Chen RW

3

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Europe PubMed Central

PubMed publication ID

8 December 2017

Leeds P

4

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8 December 2017

Chuang DM

5

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8 December 2017

publication date

1 January 2004

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8 December 2017

The Pharmacogenomics Journal

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8 December 2017

4

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Europe PubMed Central

PubMed publication ID

8 December 2017

5

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Europe PubMed Central

PubMed publication ID

8 December 2017

336-344

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PubMed publication ID

8 December 2017

Mechanisms of action of valproate: a commentatory

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

The human histone deacetylase family

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Life extension in Drosophila by feeding a drug.

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21 January 2018

Neuroprotective properties of valproate: potential benefit for AD and tauopathies

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Glyceraldehyde-3-phosphate dehydrogenase antisense oligodeoxynucleotides protect against cytosine arabinonucleoside-induced apoptosis in cultured cerebellar neurons

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Glyceraldehyde-3-phosphate dehydrogenase: Nuclear translocation participates in neuronal and nonneuronal cell death

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N -methyl- d -aspartate receptor-mediated calcium influx

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Domoic acid neurotoxicity in cultured cerebellar granule neurons is controlled preferentially by the NMDA receptor Ca(2 ) influx pathway

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Kainate-induced excitotoxicity is dependent upon extracellular potassium concentrations that regulate the activity of AMPA/KA type glutamate receptors

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Electrophysiological evidence for glial-subtype glutamate transporter functional expression in rat cerebellar granule neurons.

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase isoforms during neuronal apoptosis

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

A Novel CRM1-mediated Nuclear Export Signal Governs Nuclear Accumulation of Glyceraldehyde-3-phosphate Dehydrogenase following Genotoxic Stress

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Regulation of ER stress proteins by valproate: therapeutic implications.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

21 January 2018

Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular Distribution of Glyceraldehyde‐3‐Phosphate Dehydrogenase in Cerebellar Granule Cells Undergoing Cytosine Arabinoside‐Induced Apoptosis

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel protein complex distinct from mismatch repair binds thioguanylated DNA.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500269

7 January 2021

based on heuristic

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10.1038/SJ.TPJ.6500269

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Europe PubMed Central

PubMed publication ID

8 December 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

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