p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress (Q44945710)

7 December 2017

title

p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress (English)

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7 December 2017

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2

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7 December 2017

Arvi Jõers

1

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7 December 2017

Johanna Kase

series ordinal

3

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7 December 2017

Toivo Maimets

series ordinal

4

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7 December 2017

language of work or name

English

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publication date

1 August 2004

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7 December 2017

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7 December 2017

volume

23

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7 December 2017

issue

37

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7 December 2017

page(s)

6175-6185

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Generation of destabilized green fluorescent protein as a transcription reporter

7 December 2017

cites work

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

Post-translational modifications and activation of p53 by genotoxic stresses

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

mdm2 expression is induced by wild type p53 activity

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Cell signaling can direct either binary or graded transcriptional responses

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Noise in eukaryotic gene expression

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Stochastic patterns in globin gene expression are established prior to transcriptional activation and are clonally inherited

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Stochastic gene expression in a single cell

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Participation of the human p53 3′UTR in translational repression and activation following γ-irradiation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Cancer. p53, guardian of the genome

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

A model for p53-induced apoptosis

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Transcriptional control: rheostat converted to on/off switch

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

p53: good cop/bad cop.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

p53 mutant mice that display early ageing-associated phenotypes

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

PUMA induces the rapid apoptosis of colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207864

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207864

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Dimensions Publication ID

7 December 2017

1014751989

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