Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols. (Q44904831)

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English	Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols.	scientific article

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28 December 2019

Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols (English)

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28 December 2019

Trypanosoma cruzi

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Trypanosoma brucei

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5

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28 December 2019

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Madia Trujillo

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28 December 2019

Heike Budde

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28 December 2019

María Dolores Piñeyro

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28 December 2019

Matthias Stehr

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Leopold Flohé

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28 December 2019

Rafael Radi

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19 May 2004

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28 December 2019

Journal of Biological Chemistry

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28 December 2019

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28 December 2019

34175-34182

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28 December 2019

Induction of macrophage activation and opsonizing antibodies by Trypanosoma cruzi subpopulations

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-α and IFN-γ through a nitric oxide-dependent mechanism

1 reference

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21 January 2018

Hydrogen peroxide generation inTrypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Inducible nitric oxide synthase and nitrotyrosine in the central nervous system of mice chronically infected with Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Nitric oxide, oxidants, and protein tyrosine nitration

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Relationships between nitric oxide, nitroxyl ion, nitrosonium cation and peroxynitrite

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Peroxynitrite reaction with the reduced and the oxidized forms of lipoic acid: new insights into the reaction of peroxynitrite with thiols

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Glyceraldehyde-3-phosphate dehydrogenase inactivation by peroxynitrite.

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Rapid and irreversible inhibition of creatine kinase by peroxynitrite

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Peroxynitrite reductase activity of bacterial peroxiredoxins

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

The local electrostatic environment determines cysteine reactivity of tubulin

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin.

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

A second class of peroxidases linked to the trypanothione metabolism

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Molecular characterisation of mitochondrial and cytosolic trypanothione-dependent tryparedoxin peroxidases in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Kinetics and Redox-Sensitive Oligomerisation Reveal Negative Subunit Cooperativity in Tryparedoxin Peroxidase of Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome.

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Role of peroxidoxins in Leishmania chagasi survival. Evidence of an enzymatic defense against nitrosative stress

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Trypanosoma cruzi response to the oxidative stress generated by hydrogen peroxide.

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Dimerization of thiol-specific antioxidant and the essential role of cysteine 47.

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Dimers to doughnuts: redox-sensitive oligomerization of 2-cysteine peroxiredoxins

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Monitoring antisense oligodeoxynucleotide activity in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Trypanosoma brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes.

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

His-tagged tryparedoxin peroxidase of Trypanosoma cruzi as a tool for drug screening

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Tissue sulfhydryl groups

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Reactions of Manganese Porphyrins with Peroxynitrite and Carbonate Radical Anion

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Type II restriction endonucleases

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Cloning and characterization of three differentially expressed peroxidoxin genes from Leishmania chagasi. Evidence for an enzymatic detoxification of hydroxyl radicals

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Differential regulation of nitric oxide synthase isoforms in experimental acute chagasic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1074/JBC.M404317200

21 January 2018

Identifiers

10.1074/JBC.M404317200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15155760 AND SRC:MED&resulttype=core&format=json

28 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15155760 AND SRC:MED&resulttype=core&format=json

28 December 2019

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