De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells. (Q44799706)

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25 December 2019

title

De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells (English)

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25 December 2019

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4

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25 December 2019

author name string

Vladislav Dolgachev

1

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25 December 2019

M Sharjeel Farooqui

2

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25 December 2019

Olga I Kulaeva

3

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25 December 2019

Biserka Nagy

5

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25 December 2019

Kentaro Hanada

6

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25 December 2019

Duska Separovic

7

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25 December 2019

language of work or name

English

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publication date

12 March 2004

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Journal of Biological Chemistry

25 December 2019

published in

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25 December 2019

volume

279

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25 December 2019

issue

22

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25 December 2019

page(s)

23238-23249

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Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism

25 December 2019

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Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis

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De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis.

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Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling

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Increasing intracellular ceramide: an approach that enhances the cytotoxic response in prostate cancer cells

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FADD null mouse embryonic fibroblasts undergo apoptosis after photosensitization with the silicon phthalocyanine Pc 4.

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A role for the de novo sphingolipids in apoptosis of photosensitized cells

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Mammalian cell mutants resistant to a sphingomyelin-directed cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase

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Localization, topology, and function of the LCB1 subunit of serine palmitoyltransferase in mammalian cells.

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Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques

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Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

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Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin

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Strong and prolonged induction of c-jun and c-fos proto-oncogenes by photodynamic therapy

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Up-regulation of Hsp27 plays a role in the resistance of human colon carcinoma HT29 cells to photooxidative stress

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Production of ceramides causes apoptosis during early neural differentiation in vitro

21 January 2018

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Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases

21 January 2018

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Differential Roles of de Novo Sphingolipid Biosynthesis and Turnover in the “Burst” of Free Sphingosine and Sphinganine, and Their 1-Phosphates and N-Acyl-Derivatives, That Occurs upon Changing the Medium of Cells in Culture

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