The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53. (Q44509784)

3 December 2017

title

The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53. (English)

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3 December 2017

main subject

protein ubiquitination

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Herpes simplex virus type 1

inferred from title

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1

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3 December 2017

Roger D Everett

2

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3 December 2017

language of work or name

English

0 references

publication date

9 July 2003

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Journal of Biological Chemistry

3 December 2017

published in

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3 December 2017

volume

278

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3 December 2017

issue

38

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3 December 2017

page(s)

36596-36602

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ICP0, a regulator of herpes simplex virus during lytic and latent infection

3 December 2017

cites work

1 reference

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ICP0, ICP4, or VP16 expressed from adenovirus vectors induces reactivation of latent herpes simplex virus type 1 in primary cultures of latently infected trigeminal ganglion cells

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A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

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Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitro

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Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymes

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Mechanisms underlying ubiquitination

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ICP0 induces the accumulation of colocalizing conjugated ubiquitin

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Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins

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Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins

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Degradation of nucleosome-associated centromeric histone H3-like protein CENP-A induced by herpes simplex virus type 1 protein ICP0

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21 January 2018

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21 January 2018

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21 January 2018

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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

21 January 2018

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21 January 2018

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Herpes simplex virus 1 ICP0 co-localizes with a SUMO-specific protease

21 January 2018

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Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells

21 January 2018

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p53 De-ubiquitination: at the edge between life and death

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M300776200

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uo435oc2cjdq3kpilwoay6nk7y

30 July 2022

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Fatcat ID

release_uo435oc2cjdq3kpilwoay6nk7y

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Fatcat

https://api.fatcat.wiki/v0/release/uo435oc2cjdq3kpilwoay6nk7y

30 July 2022

mapped directly with Wikidata item

https://api.fatcat.wiki/v0/release/uo435oc2cjdq3kpilwoay6nk7y

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30 July 2022