Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia (Q44507092)

3 December 2017

title

Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia (English)

1 reference

3 December 2017

0 references

0 references

5

Weinberger DR

1 reference

3 December 2017

Cynthia Shannon Weickert

1

object named as

Weickert CS

1 reference

3 December 2017

Hyde TM

2

1 reference

3 December 2017

Lipska BK

3

1 reference

3 December 2017

Herman MM

4

1 reference

3 December 2017

Kleinman JE

6

1 reference

3 December 2017

language of work or name

English

0 references

publication date

1 June 2003

1 reference

3 December 2017

1 reference

3 December 2017

volume

8

1 reference

3 December 2017

issue

6

1 reference

3 December 2017

page(s)

592-610

1 reference

Neurotrophins and the specification of neuronal phenotype

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Functional Interactions of Neurotrophins and Neurotrophin Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Requirement for BDNF in activity-dependent survival of cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Neurotrophin regulation of cortical dendritic growth requires activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Neurotrophins regulate dendritic growth in developing visual cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Neurotrophins and neuronal plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF mRNA expression in the developing rat brain following kainic acid-induced seizure activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Expression of members of the trk family in the developing postnatal rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

The neuroanatomy and neurochemistry of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Abnormal excitatory neurotransmitter metabolism in schizophrenic brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Regionally specific neuronal pathology in untreated patients with schizophrenia: a proton magnetic resonance spectroscopic imaging study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Reduced GAP-43 mRNA in dorsolateral prefrontal cortex of patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Reduction of synaptophysin immunoreactivity in the prefrontal cortex of subjects with schizophrenia. Regional and diagnostic specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Alterations in synaptic proteins and their encoding mRNAs in prefrontal cortex in schizophrenia: a possible neurochemical basis for 'hypofrontality'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Altered levels of the synaptosomal associated protein SNAP-25 in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Dendritic spine density in schizophrenia and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Neuronal and glial somal size in the prefrontal cortex: a postmortem morphometric study of schizophrenia and Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Decreased somal size of deep layer 3 pyramidal neurons in the prefrontal cortex of subjects with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Hippocampal neurons in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

A candidate molecule approach to defining developmental pathology in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Developmental expression of brain derived neurotrophic factor mRNA by neurons of fetal and adult monkey prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Cytoarchitectonic Definition of Prefrontal Areas in the Normal Human Cortex: I. Remapping of Areas 9 and 46 using Quantitative Criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Distribution of the neurotrophins brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 in the postnatal rat brain: an immunocytochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Optimization of cRNA probe in situ hybridization methodology for localization of glucocorticoid receptor mRNA in rat brain: a detailed protocol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Somatostatin and brain-derived neurotrophic factor mRNA expression in the primate brain: decreased levels of mRNAs during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Expression of TrkB and TrkC but not BDNF mRNA in neurochemically identified interneurons in rat visual cortex in vivo and in organotypic cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Mapping the differences in the brain concentration of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in an animal model of depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Changes in the pattern of brain-derived neurotrophic factor immunoreactivity in the rat brain after acute and subchronic haloperidol treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Blockade of Endogenous Ligands of TrkB Inhibits Formation of Ocular Dominance Columns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Learning deficit in BDNF mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Multiple promoters direct tissue-specific expression of the rat BDNF gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Regulation of BDNF promoters in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Developmental regulation of brain-derived neurotrophic factor messenger RNAs transcribed from different promoters in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Multiple promoters direct stimulus and temporal specific expression of brain-derived neurotrophic factor in the somatosensory cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Distinctive four promoters collectively direct expression of brain-derived neurotrophic factor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Brain insults in rats induce increased expression of the BDNF gene through differential use of multiple promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Depresssion--emerging insights from neurobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Novel therapeutic approaches beyond the serotonin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

No linkage or linkage disequilibrium between brain-derived neurotrophic factor (BDNF) dinucleotide repeat polymorphism and schizophrenia in Irish families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Heritability of BDNF alleles and their effect on brain morphology in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Association study of schizophrenia with polymorphisms at six candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF mRNA expression during postnatal development, maturation and aging of the human prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Alterations in trkB mRNA in the human prefrontal cortex throughout the lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Peripubertal refinement of the intrinsic and associational circuitry in monkey prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: a tyrosine hydroxylase immunohistochemical analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Synaptogenesis in the prefrontal cortex of rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Developmental and stress-related changes of neurotrophic factor gene expression in an animal model of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation- and excitatory amino acid-induced injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF and NT-4, but not NT-3, promote development of inhibitory synapses in the absence of neuronal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Effects of BDNF on dopaminergic, serotonergic, and GABAergic neurons in cultures of human fetal ventral mesencephalon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

GABAA receptor subunit gene expression in human prefrontal cortex: comparison of schizophrenics and controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Anterograde transport of brain-derived neurotrophic factor and its role in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Evaluation of nigrostriatal dopaminergic function in adult / and /- BDNF mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Striatal dopamine output is compromised within /- BDNF mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Brain-derived neurotrophic factor regulates the expression of AMPA receptor proteins in neocortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-N-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Reduction of the synaptic protein rab3a in the thalamus and connecting brain regions in post-mortem schizophrenic brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accumbens in schizophrenics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

The volume of the mediodorsal thalamic nucleus in treated and untreated schizophrenics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Subnucleus-specific loss of neurons in medial thalamus of schizophrenics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Anterograde transport and trophic actions of BDNF and NT-4/5 in the developing rat visual system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Brain-derived neurotrophic factor and neurotrophin 3 in schizophrenic psychoses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

BDNF upregulation during declarative memory formation in monkey inferior temporal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Molecular cloning and expression of brain-derived neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Activation of NMDA receptors increases brain-derived neurotrophic factor (BDNF) mRNA expression in the hippocampal formation.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Transient and persistent expression of NT-3/HDNF mRNA in the rat brain during postnatal development

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Regulated neurotrophin receptor responsiveness during neuronal migrationand early differentiation.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Brain-derived neurotrophic factor requirement for activity-dependent maturation of glutamatergic synapse in developing mouse somatosensory cortex

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Decreased frontal lobe ratio of N-acetyl aspartate to choline in familial schizophrenia: a proton magnetic resonance spectroscopy study

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Synaptic innervation density is regulated by neuron-derived BDNF

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Regional distribution and developmental expression of epidermal growth factor and transforming growth factor-alpha mRNA in mouse brain by a quantitative nuclease protection assay

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Expression of brain-derived neurotrophic factor, neurotrophin-3 and their receptor messenger RNAs in monkey rhinal cortex

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Expression of Neurotrophins BDNF and NT-3, and Their Receptors in Rat Brain After Administration of Antipsychotic and Psychotrophic Agents

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Brain Derived Neurotrophic Factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Neurotrophin-3 selectively increases cultured Purkinje cell survival

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Characterization of the responses of Purkinje cells to neurotrophin treatment

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Differential expression of GABA(A) receptor subunit mRNAs and ligand binding sites in rat brain following phencyclidine administration

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

The response of human and rat fetal ventral mesencephalon in culture to the brain-derived neurotrophic factor treatment

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Alterations in nigrostriatal dopaminergic function within BDNF mutant mice

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Rab3A is required for brain-derived neurotrophic factor-induced synaptic plasticity: transcriptional analysis at the population and single-cell levels.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Postmortem assessment of thalamic nuclear volumes in subjects with schizophrenia

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Reduced number of mediodorsal and anterior thalamic neurons in schizophrenia

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements.

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Lamina-specific deficits in parvalbumin-immunoreactive varicosities in the prefrontal cortex of subjects with schizophrenia: evidence for fewer projections from the thalamus

1 reference

https://api.crossref.org/works/10.1038/SJ.MP.4001308

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001308

1 reference

3 December 2017

1 reference