Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties (Q44264337)

1 December 2017

title

Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties (English)

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1 December 2017

2

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1 December 2017

4

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1 December 2017

Joan L Buss

1

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1 December 2017

Nina Gellert

series ordinal

3

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1 December 2017

Prem Ponka

series ordinal

5

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1 December 2017

language of work or name

English

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publication date

1 January 2003

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1 December 2017

published in

Biochemical Pharmacology

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1 December 2017

volume

65

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1 December 2017

issue

2

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1 December 2017

page(s)

161-172

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Iron chelators induce apoptosis in proliferating cells

1 December 2017

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Desferrioxamine Enhances the Effects of Gamma Radiation on Clonogenic Survival and the Formation of Chromosomal Aberrations in Endothelial Cells

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Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.

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Pyridoxal isonicotinoyl hydrazone. Effective iron chelation after oral administration

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Effect of pyridoxal isonicotinoyl hydrazone and other hydrazones on iron release from macrophages, reticulocytes and hepatocytes

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Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells

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A study of the mechanism of action of pyridoxal isonicotinoyl hydrazone at the cellular level using reticulocytes loaded with non-heme 59Fe

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α-Tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation, and both lysosomal and mitochondrial destabilisation

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The effect of various chelating agents on the mobilization of iron from reticulocytes in the presence and absence of pyridoxal isonicotinoyl hydrazone

7 January 2021

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Mobilization of intracellular iron by analogs of pyridoxal isonicotinoyl hydrazone (PIH) is determined by the membrane permeability of the iron-chelator complexes

7 January 2021

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Evidence that transferrin supports cell proliferation by supplying iron for DNA synthesis

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Ferric pyridoxal isonicotinoyl hydrazone can provide iron for heme synthesis in reticulocytes

7 January 2021

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7 January 2021

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7 January 2021

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Iron chelators of the pyridoxal isonicotinoyl hydrazone class. Relationship of the lipophilicity of the apochelator to its ability to mobilize iron from reticulocytes in vitro: reappraisal of reported partition coefficients

7 January 2021

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Iron chelators of the pyridoxal isonicotinoyl hydrazone class. Relationship of the lipophilicity of the apochelator to its ability to mobilise iron from reticulocytes in vitro

7 January 2021

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10.1016/S0006-2952(02)01512-5

7 January 2021

Identifiers

DOI

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1 December 2017

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