Vigilant vectors: adeno-associated virus with a biosensor to switch on amplified therapeutic genes in specific tissues in life-threatening diseases (Q44249554)

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scientific article published in October 2002

Language	Label	Description	Also known as
English	Vigilant vectors: adeno-associated virus with a biosensor to switch on amplified therapeutic genes in specific tissues in life-threatening diseases	scientific article published in October 2002

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Vigilant vectors: adeno-associated virus with a biosensor to switch on amplified therapeutic genes in specific tissues in life-threatening diseases (English)

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Europe PubMed Central

PubMed publication ID

1 December 2017

vector-borne disease

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author name string

Yi Tang

1

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Europe PubMed Central

PubMed publication ID

1 December 2017

Kai Schmitt-Ott

2

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Europe PubMed Central

PubMed publication ID

1 December 2017

Keping Qian

3

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Europe PubMed Central

PubMed publication ID

1 December 2017

Shuntaro Kagiyama

4

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

M Ian Phillips

5

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Europe PubMed Central

PubMed publication ID

1 December 2017

publication date

1 October 2002

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Europe PubMed Central

PubMed publication ID

1 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

28

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Europe PubMed Central

PubMed publication ID

1 December 2017

2

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Europe PubMed Central

PubMed publication ID

1 December 2017

259-266

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Europe PubMed Central

PubMed publication ID

1 December 2017

Vigilant vector: heart-specific promoter in an adeno-associated virus vector for cardioprotection

1 reference

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Hypoxia inducible double plasmid system for myocardial ischemia gene therapy

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Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors

1 reference

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Prolonged reduction of high blood pressure with an in vivo, nonpathogenic, adeno-associated viral vector delivery of AT1-R mRNA antisense

1 reference

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7 January 2021

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General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

1 reference

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7 January 2021

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

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7 January 2021

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Heart-specific targeting of firefly luciferase by the myosin light chain-2 promoter and developmental regulation in transgenic mice

1 reference

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7 January 2021

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Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

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7 January 2021

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

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7 January 2021

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Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

https://api.crossref.org/works/10.1016/S1046-2023(02)00231-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

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7 January 2021

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

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7 January 2021

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

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7 January 2021

based on heuristic

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A novel, tissue-restricted zinc finger protein (HF-1b) binds to the cardiac regulatory element (HF-1b/MEF-2) in the rat myosin light-chain 2 gene

1 reference

https://api.crossref.org/works/10.1016/S1046-2023(02)00231-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A ubiquitous factor (HF-1a) and a distinct muscle factor (HF-1b/MEF-2) form an E-box-independent pathway for cardiac muscle gene expression

1 reference

https://api.crossref.org/works/10.1016/S1046-2023(02)00231-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A conserved 28-base-pair element (HF-1) in the rat cardiac myosin light-chain-2 gene confers cardiac-specific and alpha-adrenergic-inducible expression in cultured neonatal rat myocardial cells

1 reference

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7 January 2021

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The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

1 reference

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7 January 2021

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Heart-specific targeting of beta-galactosidase by the ventricle-specific cardiac myosin light chain 2 promoter using adenovirus vectors

1 reference

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7 January 2021

based on heuristic

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Analysis of tissue-specific gene delivery by recombinant adenoviruses containing cardiac-specific promoters

1 reference

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7 January 2021

based on heuristic

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Increase in Angiotensin II Type 1 Receptor Expression Immediately After Ischemia-Reperfusion in Isolated Rat Hearts

1 reference

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7 January 2021

based on heuristic

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Critical role of AT1 receptor expression after ischemia/reperfusion in isolated rat hearts: beneficial effect of antisense oligodeoxynucleotides directed at AT1 receptor mRNA.

1 reference

https://api.crossref.org/works/10.1016/S1046-2023(02)00231-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protection against ischemia/reperfusion injury and myocardial dysfunction by antisense-oligodeoxynucleotide directed at angiotensin-converting enzyme mRNA.

1 reference

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7 January 2021

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Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene

1 reference

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7 January 2021

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A regulatory system for use in gene transfer

1 reference

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7 January 2021

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Antisense inhibition and adeno-associated viral vector delivery for reducing hypertension

1 reference

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7 January 2021

based on heuristic

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

https://api.crossref.org/works/10.1016/S1046-2023(02)00231-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1016/S1046-2023(02)00231-1

7 January 2021

based on heuristic

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Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein

1 reference

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7 January 2021

based on heuristic

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Specific DNA binding of GAL4, a positive regulatory protein of yeast

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7 January 2021

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Transcription activation by the adenovirus E1a protein

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7 January 2021

based on heuristic

inferred from DOI database lookup

Attenuation of hypertension and heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense

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Pulsatile intravenous growth hormone (GH) infusion to hypophysectomized rats increases insulin-like growth factor I messenger ribonucleic acid in skeletal tissues more effectively than continuous GH infusion.

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Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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Transcriptional activation by tetracyclines in mammalian cells

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7 January 2021

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Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

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The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

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Ligand-inducible and liver-specific target gene expression in transgenic mice

1 reference

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7 January 2021

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A humanized system for pharmacologic control of gene expression

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Tetracycline staining of teeth

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7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of physiologically regulated vectors for the treatment of ischemic disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Development of a hypoxia-responsive vector for tumor-specific gene therapy

1 reference

https://api.crossref.org/works/10.1016/S1046-2023(02)00231-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Behavior of genes directly injected into the rat heart in vivo

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of "enhancer" sequences on ventricular myosin light chain-2 promoter activity in heart muscle and nonmuscle cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation

1 reference

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7 January 2021

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Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization

1 reference

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Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer

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Identifiers

10.1016/S1046-2023(02)00231-1

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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