Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosis (Q44198653)

30 November 2017

title

Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosis (English)

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30 November 2017

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2

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6

Gregory J Gores

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30 November 2017

Hajime Higuchi

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30 November 2017

Annette Grambihler

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3

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30 November 2017

Nathan Werneburg

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4

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30 November 2017

Steven F Bronk

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5

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30 November 2017

language of work or name

English

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publication date

28 October 2002

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Journal of Biological Chemistry

30 November 2017

published in

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30 November 2017

volume

278

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30 November 2017

issue

1

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30 November 2017

page(s)

454-461

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A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

30 November 2017

cites work

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Mechanisms of cholestasis

21 January 2018

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Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

21 January 2018

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The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis.

21 January 2018

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Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.

21 January 2018

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Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.

21 January 2018

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Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity

21 January 2018

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FADD/MORT1, a signal transducer that can promote cell death or cell growth.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

21 January 2018

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21 January 2018

Caspases: enemies within

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Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

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Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

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Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Inhibition of death receptor signals by cellular FLIP

21 January 2018

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FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis

21 January 2018

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I-FLICE, a Novel Inhibitor of Tumor Necrosis Factor Receptor-1- and CD-95-induced Apoptosis

21 January 2018

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Casper is a FADD- and caspase-related inducer of apoptosis

21 January 2018

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CASH, a Novel Caspase Homologue with Death Effector Domains

21 January 2018

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MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclX L and initiates cell death

21 January 2018

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CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

21 January 2018

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Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

21 January 2018

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FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

21 January 2018

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Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Regulation of lymphocyte proliferation and death by FLIP.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

The role of c-FLIP in modulation of CD95-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.

21 January 2018

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High-speed digital microscopy

21 January 2018

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1-Methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation, and neuronal apoptosis.

21 January 2018

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The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels.

21 January 2018

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Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

21 January 2018

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TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Novel bile acid derivatives induce apoptosis via a p53-independent pathway in human breast carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M209387200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209387200

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30 November 2017

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