Calcium-induced Cytochrome c release from rat brain mitochondria is altered by digitonin (Q44182769)

30 November 2017

title

Calcium-induced Cytochrome c release from rat brain mitochondria is altered by digitonin (English)

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30 November 2017

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Nickolay Brustovetsky

series ordinal

1

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30 November 2017

Ronald Jemmerson

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2

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30 November 2017

Janet M Dubinsky

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3

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30 November 2017

language of work or name

English

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publication date

1 October 2002

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30 November 2017

number of pages

4

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inferred from page(s)

published in

Neuroscience Letters

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30 November 2017

volume

332

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30 November 2017

issue

2

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30 November 2017

page(s)

91-94

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Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver

30 November 2017

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Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2 ions

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Bax directly induces release of cytochrome c from isolated mitochondria

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The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

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Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

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Bid acts on the permeability transition pore complex to induce apoptosis

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Identifiers

DOI

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30 November 2017

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