First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers (Q44138800)

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scientific article published on 8 September 2013

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English	First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers	scientific article published on 8 September 2013

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 November 2017

First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers (English)

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30 November 2017

Plasmodium falciparum

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Sebastian A. Mikolajczak

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Sebastian A Mikolajczak

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Thomas L. Richie

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Thomas L Richie

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Alan Frederick Cowman

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Alan Cowman

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30 November 2017

Stefan H I Kappe

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Stefan H I Kappe

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Christian F Ockenhouse

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Christian Ockenhouse

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D. Gray Heppner

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D Gray Heppner

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Nancy Richie

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Michele D Spring

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Michele Spring

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Lisa Ware

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Cindy Tamminga

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Ilin Chuang

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Jittawadee Murphy

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Jittawadee Murphy

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Jack Komisar

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Judy Epstein

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Erika Patricia Azorin-Vega

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Patricia de la Vega

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Megan Dowler

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Robin Nielsen

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author name string

Jason W Bennett

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Stasya Zarling

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Jack Williams

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Mark Polhemus

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Michael O'Neil

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Julie Healer

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Matthew O'Neill

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Hannah Smithers

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Olivia C Finney

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Ruobing Wang

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Urszula Krzych

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30 November 2017

language of work or name

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publication date

8 September 2013

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30 November 2017

number of pages

9

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31

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4975-4983

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30 November 2017

Global malaria mortality between 1980 and 2010: a systematic analysis

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https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites

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https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

1 reference

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Immunization of man against falciparum and vivax malaria by use of attenuated sporozoites

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

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Letter: Sporozoite induced immunity in man against an Ethiopian strain of Plasmodium falciparum

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https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Safety and clinical outcome of experimental challenge of human volunteers with Plasmodium falciparum-infected mosquitoes: an update

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Rapid effector function in CD8 memory T cells

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Multiple functions of human T cells generated by experimental malaria challenge

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4 and CD8 T cells producing IFN-gamma

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Immune mechanisms in malaria: new insights in vaccine development

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https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Advances and challenges in malaria vaccine development.

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

The RTS,S vaccine candidate for malaria

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8 T Cell Immunity

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Whole parasite vaccination approaches for prevention of malaria infection

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Preerythrocytic malaria vaccine development

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Plasmodium berghei Δp52&p36 parasites develop independent of a parasitophorous vacuole membrane in Huh-7 liver cells

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8 T cells

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Protective immunity induced with the RTS,S/AS vaccine is associated with IL-2 and TNF-α producing effector and central memory CD4 T cells

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8 T cells

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

Immunization of man against sporozite-induced falciparum malaria

1 reference

https://api.crossref.org/works/10.1016/J.VACCINE.2013.08.007

7 January 2021

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Identifiers

10.1016/J.VACCINE.2013.08.007

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

ResearchGate publication ID

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