Click Peptide concept: o-acyl isopeptide of islet amyloid polypeptide as a nonaggregative precursor molecule. (Q43972959)

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title

Click Peptide concept: o-acyl isopeptide of islet amyloid polypeptide as a nonaggregative precursor molecule (English)

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1

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author name string

Ayano Higa

2

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Naoko Abe

3

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Fukue Fukao

4

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Tomomi Kuruma

5

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Yuki Toda

6

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Youhei Sohma

7

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Yoshiaki Kiso

8

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publication date

28 April 2011

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volume

12

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issue

8

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page(s)

1216-1222

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Islet amyloid polypeptide--a novel controversy in diabetes research

30 January 2020

cites work

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On the Relation of Chronic Interstitial Pancreatitis to the Islands of Langerhans and to Diabetes Melutus

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Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

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Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

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Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

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Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

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Structure-function relationships of pre-fibrillar protein assemblies in Alzheimer's disease and related disorders

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Amyloidogenicity and cytotoxicity of islet amyloid polypeptide

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RNA aptamers generated against oligomeric Abeta40 recognize common amyloid aptatopes with low specificity but high sensitivity

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Fast Fmoc synthesis of hAmylin1-37 with pseudoproline assisted on-resin disulfide formation.

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Microwave assisted SPPS of amylin and its toxicity of the pure product to RIN-5F cells

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Efficient microwave-assisted synthesis of human islet amyloid polypeptide designed to facilitate the specific incorporation of labeled amino acids

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"Click peptide" based on the "o-acyl isopeptide method": control of A beta1-42 production from a photo-triggered A beta1-42 analogue

21 January 2018

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"Click peptides"--chemical biology-oriented synthesis of Alzheimer's disease-related amyloid beta peptide (abeta) analogues based on the "O-acyl isopeptide method".

21 January 2018

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Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept

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"Click peptide": pH-triggered in situ production and aggregation of monomer Abeta1-42.

21 January 2018

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An intramolecular O-N migration reaction on gold surfaces: toward the preparation of well-defined amyloid surfaces.

21 January 2018

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Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

21 January 2018

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Controlled in situ preparation of A beta(1-42) oligomers from the isopeptide "iso-A beta(1-42)", physicochemical and biological characterization

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Switch peptides in statu nascendi: induction of conformational transitions relevant to degenerative diseases

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Development of O-acyl isopeptide method.

21 January 2018

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Ester to amide switch peptides provide a simple method for preparing monomeric islet amyloid polypeptide under physiologically relevant conditions and facilitate investigations of amyloid formation

21 January 2018

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O-acyl isopeptide method: efficient synthesis of isopeptide segment and application to racemization-free segment condensation

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Amylin proprotein processing generates progressively more amyloidogenic peptides that initially sample the helical state

21 January 2018

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Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide

21 January 2018

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Solution state structures of human pancreatic amylin and pramlintide

21 January 2018

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Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

21 January 2018

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Human islet amyloid polypeptide monomers form ordered beta-hairpins: a possible direct amyloidogenic precursor

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CBIC.201100025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21538760 AND SRC:MED&resulttype=core&format=json

30 January 2020

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