Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme. (Q43957783)

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English	Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.	scientific article

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9 December 2019

Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11950837 AND SRC:MED&resulttype=core&format=json

9 December 2019

cooperative behavior

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Ioannis Zaganas

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9 December 2019

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Andreas Plaitakis

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11 April 2002

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9 December 2019

Journal of Biological Chemistry

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9 December 2019

277

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9 December 2019

26422-26428

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9 December 2019

Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain.

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Neurological disorders associated with deficiency of glutamate dehydrogenase

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

The human glutamate dehydrogenase gene family: gene organization and structural characterization

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Cassette mutagenesis of lysine 130 of human glutamate dehydrogenase. An essential residue in catalysis

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Identification of the GTP binding site of human glutamate dehydrogenase by cassette mutagenesis and photoaffinity labeling

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Identification of a peptide of the guanosine triphosphate binding site within brain glutamate dehydrogenase isoproteins using 8-azidoguanosine triphosphate

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Novel missense mutations in the glutamate dehydrogenase gene in the congenital hyperinsulinism-hyperammonemia syndrome

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Novel missense mutations outside the allosteric domain of glutamate dehydrogenase are prevalent in European patients with the congenital hyperinsulinism-hyperammonemia syndrome

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Hyperinsulinism and hyperammonemia syndrome: report of twelve unrelated patients

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Nerve tissue-specific human glutamate dehydrogenase that is thermolabile and highly regulated by ADP.

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Molecular basis and characterization of the hyperinsulinism/hyperammonemia syndrome: predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene. HI/HA Contributing Investigators

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

L-glutamate dehydrogenases: distribution, properties and mechanism.

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Crystallization and Characterization of Bovine Liver Glutamate Dehydrogenase

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

Hyperinsulinism-hyperammonemia syndrome caused by mutant glutamate dehydrogenase accompanied by novel enzyme kinetics

1 reference

https://api.crossref.org/works/10.1074/JBC.M200022200

21 January 2018

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10.1074/JBC.M200022200

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11950837 AND SRC:MED&resulttype=core&format=json

9 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11950837 AND SRC:MED&resulttype=core&format=json

9 December 2019

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