Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase (Q43936779)

28 November 2017

title

Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase (English)

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28 November 2017

12

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28 November 2017

Christopher J Wilkinson

object named as

Christopher J Wilkinson

2

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Carmen Méndez

object named as

Carmen Mendez

9

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author name string

Paul F Long

1

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28 November 2017

Christian P Bisang

3

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28 November 2017

Jesús Cortés

4

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28 November 2017

Nicholas Dunster

5

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28 November 2017

Marko Oliynyk

6

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28 November 2017

Ellen McCormick

7

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28 November 2017

Hamish McArthur

8

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28 November 2017

José A Salas

10

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28 November 2017

James Staunton

11

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28 November 2017

language of work or name

English

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publication date

1 March 2002

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28 November 2017

published in

Molecular Microbiology

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28 November 2017

volume

43

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28 November 2017

issue

5

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28 November 2017

page(s)

1215-1225

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Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase

28 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

A comprehensive set of sequence analysis programs for the VAX

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Modular organization of genes required for complex polyketide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Analysis of seven genes from the eryAI-eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Genetic Contributions to Understanding Polyketide Synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Engineered biosynthesis of a complete macrolactone in a heterologous host

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Production of a novel polyketide through the construction of a hybrid polyketide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Substrate specificity of the loading didomain of the erythromycin polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Correlation of the avermectin polyketide synthase genes to the avermectin structure. Implications for designing novel avermectins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Engineering broader specificity into an antibiotic-producing polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Streptomyces antibioticus contains at least three oleandomycin-resistance determinants, one of which shows similarity with proteins of the ABC-transporter superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Construction of new vectors for high-level expression in actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

The Staden sequence analysis package

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Compilation and analysis of DNA sequences associated with apparent streptomycete promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Origin of starter units for erythromycin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Conversion of a beta-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1365-2958.2002.02815.X

Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.53.502

Novel erythromycins from a recombinant Saccharopolyspora erythraea strain NRRL 2338 pIG1. I. Fermentation, isolation and biological activity

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.51.1029

Identifiers

DOI

10.1046/J.1365-2958.2002.02815.X

1 reference

28 November 2017

1 reference