c-Myc initiates illegitimate replication of the ribonucleotide reductase R2 gene (Q43882805)

27 November 2017

title

c-Myc initiates illegitimate replication of the ribonucleotide reductase R2 gene (English)

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27 November 2017

Kuschak TI

1

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27 November 2017

Kuschak BC

2

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27 November 2017

Taylor CL

3

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27 November 2017

Wright JA

4

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27 November 2017

Wiener F

5

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27 November 2017

Mai S

6

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27 November 2017

language of work or name

English

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publication date

1 January 2002

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27 November 2017

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27 November 2017

volume

21

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27 November 2017

issue

6

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27 November 2017

page(s)

909-920

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Binding of myc proteins to canonical and noncanonical DNA sequences

27 November 2017

cites work

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Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea

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Double minute chromosomes can be produced from precursors derived from a chromosomal deletion

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Elevated c-myc expression facilitates the replication of SV40 DNA in human lymphoma cells

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Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix

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Transient excess of MYC activity can elicit genomic instability and tumorigenesis

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Reversible tumorigenesis by MYC in hematopoietic lineages

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The mammalian dihydrofolate reductase locus

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Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting

21 January 2018

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Allele-specific replication timing of imprinted gene regions

21 January 2018

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Genetics of human cancer

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

21 January 2018

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Molecular cloning and chromosomal localization of the human cyclin C (CCNC) and cyclin E (CCNE) genes: deletion of the CCNC gene in human tumors

21 January 2018

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c-Myc overexpression uncouples DNA replication from mitosis

21 January 2018

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

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Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells

21 January 2018

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c-Myc binds to 5' flanking sequence motifs of the dihydrofolate reductase gene in cellular extracts: role in proliferation

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The c-myc protein represses the lambda 5 and TdT initiators.

21 January 2018

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Genomic instability in MycER-activated Rat1A-MycER cells

21 January 2018

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Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression

21 January 2018

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Unstable and stable CAD gene amplification: importance of flanking sequences and nuclear environment in gene amplification

21 January 2018

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Formation of large deletions by illegitimate recombination in the HPRT gene of primary human fibroblasts

21 January 2018

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Interstitial deletions and intrachromosomal amplification initiated from a double-strand break targeted to a mammalian chromosome

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Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles

21 January 2018

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Formation of an inverted duplication can be an initial step in gene amplification

21 January 2018

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Asynchronous replication of imprinted genes is established in the gametes and maintained during development

21 January 2018

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Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks

21 January 2018

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Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells

21 January 2018

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Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells

21 January 2018

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Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase

21 January 2018

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Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

21 January 2018

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Lagging-Strand, Early-Labelling, and Two-Dimensional Gel Assays Suggest Multiple Potential Initiation Sites in the Chinese Hamster Dihydrofolate Reductase Origin

21 January 2018

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Protein-DNA interactions at the major and minor promoters of the divergently transcribed dhfr and rep3 genes during the Chinese hamster ovary cell cycle

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Refinement of the DNA Marker Maps of Mouse Chromosome 12

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Induction of large DNA palindrome formation in yeast: implications for gene amplification and genome stability in eukaryotes

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7 January 2021

Normal and c-Myc-promoted human keratinocyte differentiation both occur via a novel cell cycle involving cellular growth and endoreplication

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7 January 2021

The replication activity of SV40 DNA correlates with the level of c-myc expression in human tumor cell lines

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https://api.crossref.org/works/10.1038/SJ.ONC.1205145

7 January 2021

The ribonucleotide reductase R2 gene is a non-transcribed target of c-Myc-induced genomic instability

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205145

7 January 2021

Overexpression of c-myc precedes amplification of the gene encoding dihydrofolate reductase

1 reference

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The organization and amplification of two chromosomal domains containing Drosophila chorion genes

1 reference

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Identifiers

DOI

10.1038/SJ.ONC.1205145

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Dimensions Publication ID

27 November 2017

1052617073

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1 reference