Engineered biosynthesis of novel polyenes: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis. (Q43672870)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

title

Engineered biosynthesis of novel polyenes: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Pimaricin, streptomyces chattanoogensis

1 reference

inferred from

reverse claim

Streptomyces natalensis

1 reference

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

author name string

M V Mendes

1

1 reference

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9 November 2019

E Recio

2

1 reference

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9 November 2019

R Fouces

3

1 reference

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9 November 2019

R Luiten

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

J F Martín

5

1 reference

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9 November 2019

publication date

1 July 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

full work available at URL

9 November 2019

http://www.cell.com/article/S1074552101000333/pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/s1074-5521(01)[email protected]

published in

Chemistry and Biology

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9 November 2019

volume

8

1 reference

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9 November 2019

issue

7

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9 November 2019

page(s)

635-644

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9 November 2019

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/s1074-5521(01)[email protected]

access restriction status

open access

1 reference

inferred from online access status

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The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.

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7 January 2021

A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis

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Genetic Contributions to Understanding Polyketide Synthases

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Modular organization of genes required for complex polyketide biosynthesis

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Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases

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Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis

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Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome

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A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis byStreptomyces antibioticus

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Characterization and expression of a P-450-like mycinamicin biosynthesis gene using a novel Micromonospora-Escherichia coli shuttle cosmid vector

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Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin

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Cloning and heterologous expression of the epothilone gene cluster.

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7 January 2021

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90

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Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae.

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Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase

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New derivatives of the Streptomyces temperate phage phi C31 useful for the cloning and functional analysis of Streptomyces DNA.

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Organization and expression of genes involved in the biosynthesis of antibiotics and other secondary metabolites

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Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.

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7 January 2021

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