Cytochrome c release occurs via Ca2 -dependent and Ca2 -independent mechanisms that are regulated by Bax. (Q43551075)

24 November 2017

title

Cytochrome c release occurs via Ca2 -dependent and Ca2 -independent mechanisms that are regulated by Bax. (English)

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24 November 2017

3

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4

Orrenius S

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24 November 2017

Gogvadze V

1

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Robertson JD

series ordinal

2

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24 November 2017

language of work or name

English

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publication date

22 March 2001

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Journal of Biological Chemistry

24 November 2017

published in

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volume

276

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issue

22

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24 November 2017

page(s)

19066-19071

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

24 November 2017

cites work

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Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts

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Hypotonic fragility of outer membrane and activation of external pathway of NADH oxidation in rat liver mitochondria are increased with age.

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Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart

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Bcl-2 family: life-or-death switch

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2 ions

21 January 2018

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Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

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Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

21 January 2018

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

21 January 2018

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Expression and purification of full-length human Bax alpha.

21 January 2018

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

21 January 2018

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The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

21 January 2018

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Bid acts on the permeability transition pore complex to induce apoptosis

21 January 2018

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PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

21 January 2018

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Release of cytochrome c from liver mitochondria during permeability transition.

21 January 2018

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Mitochondria as all-round players of the calcium game

21 January 2018

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Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

21 January 2018

1 reference

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Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M100614200

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24 November 2017

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