DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. (Q43267407)

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9 February 2020

title

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction (English)

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Achim Leutz

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Miguel Andrade

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Sten Eirik W Jacobsen

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Frank Rosenbauer

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Rudolf Jaenisch

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Marco Prinz

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Claus Nerlov

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author name string

Ann-Marie Bröske

1

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Lena Vockentanz

2

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Shabnam Kharazi

3

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Elena Mancini

5

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Marina Scheller

6

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Christiane Kuhl

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Andreas Enns

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language of work or name

English

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publication date

4 October 2009

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9 February 2020

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volume

41

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issue

11

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9 February 2020

page(s)

1207-1215

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Epigenetic therapy of cancer: past, present and future

9 February 2020

cites work

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12 December 2020

Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates.

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Sensitive assay systems for detection of hemoglobin with 2,7-diaminofluorene: histochemistry and colorimetry for erythrodifferentiation

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Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

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B lymphocyte-specific, Cre-mediated mutagenesis in mice

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MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

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Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

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Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

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Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

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Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

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12 December 2020

The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

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12 December 2020

Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.

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12 December 2020

Identification of Flt3 lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

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12 December 2020

Lineage-specific transcription factors in multipotent hematopoietic progenitors: a little bit goes a long way.

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12 December 2020

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

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12 December 2020

An erythroid specific enhancer upstream to the gene encodin the cell-type specific transcription factor GATA-1

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12 December 2020

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

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12 December 2020

Stepwise reprogramming of B cells into macrophages

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12 December 2020

Transcription factors in myeloid development: balancing differentiation with transformation.

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12 December 2020

Establishment of methylation-sensitive-representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors

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12 December 2020

Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector

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12 December 2020

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

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12 December 2020

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

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12 December 2020

In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

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12 December 2020

Unraveling epigenetic regulation in embryonic stem cells

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12 December 2020

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

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12 December 2020

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

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12 December 2020

Induction of Tumors in Mice by Genomic Hypomethylation

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12 December 2020

Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A

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12 December 2020

Transcriptional control of early B cell development

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12 December 2020

Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation.

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12 December 2020

Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia

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12 December 2020

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

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12 December 2020

Diversification of haematopoietic stem cells to specific lineages.

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12 December 2020

Transcription of IAP endogenous retroviruses is constrained by cytosine methylation

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12 December 2020

c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.

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12 December 2020

Inducible gene targeting in mice

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12 December 2020

Stem cell research: paths to cancer therapies and regenerative medicine

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12 December 2020

GATA-1 Converts Lymphoid and Myelomonocytic Progenitors into the Megakaryocyte/Erythrocyte Lineages

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12 December 2020

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

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12 December 2020

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

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12 December 2020

Genetic networks that regulate B lymphopoiesis

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12 December 2020

Histone acetylation and DNA demethylation of B cells result in a Hodgkin-like phenotype.

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12 December 2020

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

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12 December 2020

Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors

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12 December 2020

Permutation-validated principal components analysis of microarray data

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12 December 2020

Genome-scale DNA methylation maps of pluripotent and differentiated cells

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12 December 2020

Identifiers

DOI

10.1038/NG.463

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19801979 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 February 2020

1032558981

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1 reference