Epalrestat increases glutathione, thioredoxin, and heme oxygenase-1 by stimulating Nrf2 pathway in endothelial cells (Q43047088)

12 November 2017

Epalrestat increases glutathione, thioredoxin, and heme oxygenase-1 by stimulating Nrf2 pathway in endothelial cells (English)

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12 November 2017

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Kaori Yama

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12 November 2017

Keisuke Sato

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12 November 2017

Natsuki Abe

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12 November 2017

Yu Murao

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12 November 2017

Ryosuke Tatsunami

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12 November 2017

Yoshiko Tampo

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12 November 2017

10 December 2014

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12 November 2017

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12 November 2017

87-96

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describes a project that uses

12 November 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4309844/fullTextXML

inferred from PubMed Central ID database lookup

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26 May 2018

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26 May 2018

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26 May 2018

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26 May 2018

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26 May 2018

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26 May 2018

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26 May 2018

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Thioredoxin-1 promotes anti-inflammatory macrophages of the M2 phenotype and antagonizes atherosclerosis

26 May 2018

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Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure

16 August 2018

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Aldose reductase inhibitor, epalrestat, reduces lipid hydroperoxides in type 2 diabetes.

16 August 2018

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Paraquat-induced oxidative stress and dysfunction of the glutathione redox cycle in pulmonary microvascular endothelial cells

16 August 2018

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Selective modification of glutathione metabolism

16 August 2018

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12 December 2020

Drug discovery and development focusing on existing medicines: drug re-profiling strategy

1 reference

12 December 2020

Characterization of aldose reductase and aldehyde reductase from rat testis

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12 December 2020

Effect of epalrestat, an aldose reductase inhibitor, on the generation of oxygen-derived free radicals in neutrophils from streptozotocin-induced diabetic rats

1 reference

12 December 2020

PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells

1 reference

12 December 2020

Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic n

1 reference

12 December 2020

Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase

1 reference

12 December 2020

Intracoronary infusion of reduced glutathione improves endothelial vasomotor response to acetylcholine in human coronary circulation

1 reference

12 December 2020

Reversal of diabetic cataract by sorbinil, an aldose reductase inhibitor

1 reference

12 December 2020

Determination of the number of endothelial cells in culture using an acid phosphatase assay

1 reference

12 December 2020

Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients

1 reference

12 December 2020

10.1016/J.REDOX.2014.12.002

Identifiers

DOI

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12 November 2017

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12 November 2017

PubMed publication ID

25529839

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