Characterisation and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study. (Q43002665)

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scientific article published on 29 June 2010

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English	Characterisation and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study.	scientific article published on 29 June 2010

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6 February 2020

Characterisation and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study (English)

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6 February 2020

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6 February 2020

Nigel J. Clayden

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6 February 2020

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Peter Belton

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6 February 2020

Kathrin Nollenberger

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6 February 2020

Mike Reading

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6 February 2020

Duncan Q M Craig

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6 February 2020

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29 June 2010

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6 February 2020

Pharmaceutical Research

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6 February 2020

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6 February 2020

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6 February 2020

1869-1883

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6 February 2020

Application of melt extrusion in the development of a physically and chemically stable high-energy amorphous solid dispersion of a poorly water-soluble drug

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A mechanistic investigation of an amorphous pharmaceutical and its solid dispersions, part II: molecular mobility and activation thermodynamic parameters

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Drug-polymer interaction and its significance on the physical stability of nifedipine amorphous dispersion in microparticles of an ammonio methacrylate copolymer and ethylcellulose binary blend

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Selection of excipients for melt extrusion with two poorly water-soluble drugs by solubility parameter calculation and thermal analysis.

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Miscibility of nifedipine and hydrophilic polymers as measured by (1)H-NMR spin-lattice relaxation.

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Increased physical stability and improved dissolution properties of itraconazole, a class II drug, by solid dispersions that combine fast- and slow-dissolving polymers

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Physicochemical considerations in the preparation of amorphous ritonavir-poly(ethylene glycol) 8000 solid dispersions

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Melt extrusion: from process to drug delivery technology

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Quantitative Analytical Method for Determination of Drugs Dispersed in Polymers Using Differential Scanning Calorimetry

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Identifiers

10.1007/S11095-010-0185-8

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Europe PubMed Central

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6 February 2020

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6 February 2020

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