Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways (Q42835042)

8 November 2017

title

Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways (English)

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8 November 2017

Rusyn EV

1

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8 November 2017

Reynolds ER

2

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8 November 2017

Shao H

3

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8 November 2017

Grana TM

4

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8 November 2017

Chan TO

5

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8 November 2017

Andres DA

6

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8 November 2017

Cox AD

7

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8 November 2017

language of work or name

English

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publication date

1 September 2000

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8 November 2017

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8 November 2017

volume

19

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8 November 2017

issue

41

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8 November 2017

page(s)

4685-4694

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Increasing complexity of Ras signaling.

8 November 2017

cites work

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Construction and applications of a highly transmissible murine retrovirus shuttle vector

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The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes

21 January 2018

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Biological assays for Ras transformation

21 January 2018

1 reference

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Biological assays for cellular transformation

21 January 2018

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Protein prenylation: more than just glue?

21 January 2018

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Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

21 January 2018

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Analysis of Ras protein expression in mammalian cells

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Transcriptional regulation by MAP kinases

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Cell cycle: routine role for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

21 January 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

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Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.

21 January 2018

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TC21 causes transformation by Raf-independent signaling pathways

21 January 2018

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

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Ras-mediated transcription activation: analysis by transient cotransfection assays

21 January 2018

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R-Ras is regulated by activators and effectors distinct from those that control Ras function

21 January 2018

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The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

21 January 2018

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R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells

21 January 2018

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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

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Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

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Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

21 January 2018

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The activation of phosphatidylinositol 3-kinase by Ras

21 January 2018

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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

21 January 2018

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RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

21 January 2018

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How do small GTPase signal transduction pathways regulate cell cycle entry?

21 January 2018

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21 January 2018

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R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral.

21 January 2018

1 reference

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Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival

21 January 2018

1 reference

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Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1

21 January 2018

1 reference

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An essential role for Rac in Ras transformation

21 January 2018

1 reference

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A role for Rho in Ras transformation

21 January 2018

1 reference

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The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

1 reference

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Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Biochemical characterization of the Ras-related GTPases Rit and Rin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Signaling pathways in Ras-mediated tumorigenicity and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Stimulation of gene induction and cell growth by the Ras effector Rlf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Integrin activation by R-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformation

21 January 2018

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21 January 2018

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7 January 2021

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

7 January 2021

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

7 January 2021

Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

7 January 2021

Farnesyltransferase inhibitors: targeting the molecular basis of cancer

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

7 January 2021

DsbG, a protein disulfide isomerase with chaperone activity

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1203836

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203836

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Dimensions Publication ID

8 November 2017

1020809191

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1 reference