A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins (Q42810812)

7 November 2017

title

A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins (English)

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7 November 2017

N Asai

1

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7 November 2017

H Murakami

series ordinal

2

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7 November 2017

T Iwashita

series ordinal

3

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7 November 2017

M Takahashi

series ordinal

4

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7 November 2017

language of work or name

English

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publication date

1 July 1996

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

271

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7 November 2017

issue

30

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7 November 2017

page(s)

17644-17649

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Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

7 November 2017

cites work

1 reference

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Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.

21 January 2018

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A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

21 January 2018

1 reference

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Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B

21 January 2018

1 reference

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Mutations of the RET proto-oncogene in Hirschsprung's disease

21 January 2018

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Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease

21 January 2018

1 reference

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Oncogenic activation of the ret protooncogene in thyroid cancer

21 January 2018

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Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.271.30.17644

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.271.30.17644

Loss of function effect of RET mutations causing Hirschsprung disease.

21 January 2018

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Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

21 January 2018

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Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

21 January 2018

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Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

21 January 2018

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A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes

21 January 2018

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Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

21 January 2018

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Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex

21 January 2018

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

1 reference

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 January 2018

1 reference

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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

21 January 2018

1 reference

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Tyrosines outside the kinase core and dimerization are required for the mitogenic activity of RET/ptc2.

21 January 2018

1 reference

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An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

21 January 2018

1 reference

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PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.30.17644

1 reference

7 November 2017

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