Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. (Q42779021)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292710 AND SRC:MED&resulttype=core&format=json

2 March 2020

title

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life (English)

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2 March 2020

3

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2 March 2020

Jianxin Fu

6

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2 March 2020

author name string

Paul R Hess

1

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2 March 2020

David R Rawnsley

2

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2 March 2020

Yiqing Yang

4

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2 March 2020

Daniel T Sweet

5

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2 March 2020

Brett Herzog

7

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2 March 2020

MinMin Lu

8

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2 March 2020

Bernhard Nieswandt

9

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2 March 2020

Guillermo Oliver

10

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2 March 2020

Taija Makinen

11

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2 March 2020

Lijun Xia

12

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2 March 2020

Mark L Kahn

13

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2 March 2020

language of work or name

English

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publication date

1 January 2014

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Journal of Clinical Investigation

2 March 2020

published in

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volume

124

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2 March 2020

issue

1

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2 March 2020

page(s)

273-284

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Platelet activation receptor CLEC-2 regulates blood/lymphatic vessel separation by inhibiting proliferation, migration, and tube formation of lymphatic endothelial cells

2 March 2020

cites work

1 reference

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Hemostatic properties of the lymph: relationships with occlusion and thrombosis

27 May 2018

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Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration

27 May 2018

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CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.

27 May 2018

1 reference

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Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves

27 May 2018

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Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice

27 May 2018

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Platelets: covert regulators of lymphatic development

27 May 2018

1 reference

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Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets.

27 May 2018

1 reference

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Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

27 May 2018

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Platelets play an essential role in separating the blood and lymphatic vasculatures during embryonic angiogenesis

27 May 2018

1 reference

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Lymphangiogenesis: Molecular mechanisms and future promise

27 May 2018

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Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.

27 May 2018

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Terminal part of thoracic duct: high-resolution US imaging

27 May 2018

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Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis

27 May 2018

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Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target

27 May 2018

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Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

27 May 2018

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Platelet activation and atherothrombosis

27 May 2018

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The growing complexity of platelet aggregation

27 May 2018

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R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

27 May 2018

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Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.

27 May 2018

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A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.

27 May 2018

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Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.

27 May 2018

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27 May 2018

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Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1.

27 May 2018

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Prox1 function is crucial for mouse lens-fibre elongation

27 May 2018

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Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

27 May 2018

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The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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Pressure waves and gradients in the canine thoracic duct

27 May 2018

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27 May 2018

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Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation

16 August 2018

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Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor

16 August 2018

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12 December 2020

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

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12 December 2020

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

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12 December 2020

Prox1 function is required for the development of the murine lymphatic system

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12 December 2020

Coagulation properties of human thoracic duct lymph

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12 December 2020

A study of the gross, microscopic and functional anatomy of the thoracic duct and the lympho-venous junction

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12 December 2020

Pressure within the thoracic duct modulates lymph composition

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12 December 2020

Identifiers

DOI

10.1172/JCI70422

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292710 AND SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292710 AND SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

24292710

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292710 AND SRC:MED&resulttype=core&format=json