Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat. (Q42651287)

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21 January 2020

title

Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat (English)

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21 January 2020

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1

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21 January 2020

author name string

Simona Occhi

2

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21 January 2020

Piera Calamita

3

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21 January 2020

Vera Volpi

4

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21 January 2020

Eric Blanc

5

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21 January 2020

Bernard Charroux

6

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21 January 2020

Julien Royet

7

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21 January 2020

Manolis Fanto

8

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21 January 2020

language of work or name

English

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publication date

28 January 2011

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21 January 2020

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volume

30

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21 January 2020

issue

5

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21 January 2020

page(s)

945-958

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Native Functions of the Androgen Receptor Are Essential to Pathogenesis in a Drosophila Model of Spinobulbar Muscular Atrophy

21 January 2020

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Rere controls retinoic acid signalling and somite bilateral symmetry

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The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie

27 May 2018

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Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells

27 May 2018

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Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice.

27 May 2018

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Warts is required for PI3K-regulated growth arrest, autophagy, and autophagic cell death in Drosophila

27 May 2018

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Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain

27 May 2018

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Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila

27 May 2018

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Fat and expanded act in parallel to regulate growth through warts

27 May 2018

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Drosophila brakeless interacts with atrophin and is required for tailless-mediated transcriptional repression in early embryos

27 May 2018

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Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?

27 May 2018

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The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network

27 May 2018

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Functional architecture of atrophins

27 May 2018

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Delineation of a Fat tumor suppressor pathway

27 May 2018

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Polyglutamine neurodegenerative diseases and regulation of transcription: assembling the puzzle

27 May 2018

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Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors

27 May 2018

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

27 May 2018

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

27 May 2018

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New insights into Fat cadherins

27 May 2018

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Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

27 May 2018

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A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen.

27 May 2018

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Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis

27 May 2018

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27 May 2018

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Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein

27 May 2018

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Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

27 May 2018

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

27 May 2018

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27 May 2018

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Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects

27 May 2018

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27 May 2018

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Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

27 May 2018

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The Drosophila cyclin D-Cdk4 complex promotes cellular growth

27 May 2018

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Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA.

27 May 2018

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The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily

27 May 2018

1 reference

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Neurodegeneration by polyglutamine Atrophin is not rescued by induction of autophagy.

27 May 2018

1 reference

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A new allele uncovers the role of echinus in the control of ommatidial rotation in the Drosophila eye.

16 August 2018

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Proteomic analysis of steroid-triggered autophagic programmed cell death during Drosophila development.

16 August 2018

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The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance

16 August 2018

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Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins

16 August 2018

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Atrophin contributes to the negative regulation of epidermal growth factor receptor signaling in Drosophila

16 August 2018

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The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors.

16 August 2018

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Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration

16 August 2018

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Spatiotemporal gene expression targeting with the TARGET and gene-switch systems in Drosophila

16 August 2018

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The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor.

16 August 2018

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16 August 2018

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Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes

16 August 2018

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Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21278706

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2011.1

1 reference

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21 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21278706 AND SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

21278706

1 reference