Coagulation factor V(A2440G) causes east Texas bleeding disorder via TFPIα. (Q42572887)

2 November 2017

Coagulation factor V(A2440G) causes east Texas bleeding disorder via TFPIα. (English)

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blood coagulation disease

2 November 2017

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Lisa M Vincent

1

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2 November 2017

Sinh Tran

2

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2 November 2017

Ruzica Livaja

3

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2 November 2017

Tracy A Bensend

4

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2 November 2017

Dianna M Milewicz

5

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2 November 2017

Björn Dahlbäck

6

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2 November 2017

language of work or name

English

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publication date

27 August 2013

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Journal of Clinical Investigation

2 November 2017

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2 November 2017

123

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2 November 2017

9

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2 November 2017

3777-3787

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The C-terminus of tissue factor pathway inhibitor α is required for its interaction with factors V and Va

2 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

A bipartite autoinhibitory region within the B-domain suppresses function in factor V

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Hemostatic properties of a TFPI antibody

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Tissue factor pathway inhibitor: structure-function

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

TFPIβ is the GPI-anchored TFPI isoform on human endothelial cells and placental microsomes

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

The molecular basis of factor V and VIII procofactor activation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Advances in understanding pathogenic mechanisms of thrombophilic disorders

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Aligning multiple genomic sequences with the threaded blockset aligner

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Factor V and thrombotic disease: description of a janus-faced protein

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Amino acid sequence and carbohydrate structure of a recombinant human tissue factor pathway inhibitor expressed in Chinese hamster ovary cells: one N-and two O-linked carbohydrate chains are located between Kunitz domains 2 and 3 and one N-linked ca

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Post-translational requirements for functional factor V and factor VIII secretion in mammalian cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

The mechanism of inactivation of human factor V and human factor Va by activated protein C

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Characterization of Factor V activation intermediates

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

The adsorption of blood coagulation factors II, VII, IX and X from human plasma to aluminium hydroxide.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Complete cDNA and derived amino acid sequence of human factor V

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Cloning of cDNAs coding for the heavy chain region and connecting region of human factor V, a blood coagulation factor with four types of internal repeats

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Structure of the gene for human coagulation factor V

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Effects of prothrombin on the individual activated protein C-mediated cleavages of coagulation factor Va.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Coagulation factor V and thrombophilia: background and mechanisms.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Enhanced rate of cleavage at Arg-306 and Arg-506 in coagulation factor Va by Gla domain-mutated human-activated protein C.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Functional characterization of recombinant FV Hong Kong and FV Cambridge.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

A model for the stoichiometric regulation of blood coagulation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Mechanism of factor VIIa-dependent coagulation in hemophilia blood

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Characterization of a novel autosomal dominant bleeding disorder in a large kindred from east Texas

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Posttranslational sulfation of factor V is required for efficient thrombin cleavage and activation and for full procoagulant activity

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Factor V is complexed with multimerin in resting platelet lysates and colocalizes with multimerin in platelet alpha-granules

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Molecular weight of undegraded plasma factor V.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754264

Thrombin functions during tissue factor-induced blood coagulation

16 August 2018

1 reference

12 December 2020

Isolation and characterization of single chain bovine factor V

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12 December 2020

Purification and characterization of human coagulation factor V

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12 December 2020

Thrombin-catalyzed activation of human coagulation factor V

1 reference

12 December 2020

Radioimmunoassay of factor V in human plasma and platelets

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12 December 2020

Vectors used for expression in mammalian cells

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12 December 2020

Multimerin: a series of large disulfide-linked multimeric proteins within platelets

1 reference

12 December 2020

Evaluation of the Initiation Phase of Blood Coagulation Using Ultrasensitive Assays for Serine Proteases

1 reference

12 December 2020

Protein C Activation and Factor Va Inactivation on Human Umbilical Vein Endothelial Cells

1 reference

12 December 2020

Megakaryocytes endocytose and subsequently modify human factor V in vivo to form the entire pool of a unique platelet-derived cofactor

1 reference

12 December 2020

Localization of the gene encoding human factor V to chromosome 1q21-25

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI69091

1 reference

2 November 2017

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2 November 2017

PubMed publication ID

23979162

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